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Dereplication of microbial metabolites through database search of mass spectra

Natural products have traditionally been rich sources for drug discovery. In order to clear the road toward the discovery of unknown natural products, biologists need dereplication strategies that identify known ones. Here we report DEREPLICATOR+, an algorithm that improves on the previous approache...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Mohimani, Hosein, Gurevich, Alexey, Shlemov, Alexander, Mikheenko, Alla, Korobeynikov, Anton, Cao, Liu, Shcherbin, Egor, Nothias, Louis-Felix, Dorrestein, Pieter C., Pevzner, Pavel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168521/
https://ncbi.nlm.nih.gov/pubmed/30279420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06082-8
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