Small molecule inhibitors and a kinase-dead expressing mouse model demonstrate that the kinase activity of Chk1 is essential for mouse embryos and cancer cells

per Muralidharan, Somsundar V, Nilsson, Lisa M, Lindberg, Mattias F, Nilsson, Jonas A
Publicat a Life Sci Alliance (2020)

BET bromodomain inhibitor HMBA synergizes with MEK inhibition in treatment of malignant glioma

per Funck-Brentano, Elisa, Vizlin-Hodzic, Dzeneta, Nilsson, Jonas A., Nilsson, Lisa M.
Publicat a Epigenetics (2020)

Mouse Genetics Suggests Cell-Context Dependency for Myc-Regulated Metabolic Enzymes during Tumorigenesis

per Nilsson, Lisa M., Plym Forshell, Tacha Zi, Rimpi, Sara, Kreutzer, Christiane, Pretsch, Walter, Bornkamm, Georg W., Nilsson, Jonas A.
Publicat 2012

Embryonic Expression and Function of the Xenopus Ink4d Cyclin D-Dependent Kinase Inhibitor

per Doherty, Joanne R., Nilsson, Lisa M., Kuliyev, Emin, Zhu, Haiqing, Matthew, Rose, Cleveland, John L., Mead, Paul E., Roussel, Martine F.
Publicat 2014

Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model

per Jespersen, Henrik, Lindberg, Mattias F., Donia, Marco, Söderberg, Elin M. V., Andersen, Rikke, Keller, Ulrich, Ny, Lars, Svane, Inge Marie, Nilsson, Lisa M., Nilsson, Jonas A.
Publicat a Nat Commun (2017)

BET bromodomain inhibitors synergize with ATR inhibitors in melanoma

per Muralidharan, Somsundar Veppil, Einarsdottir, Berglind Osk, Bhadury, Joydeep, Lindberg, Mattias F, Wu, Jin, Campeau, Eric, Bagge, Roger Olofsson, Stierner, Ulrika, Ny, Lars, Nilsson, Lisa M, Nilsson, Jonas A
Publicat a Cell Death Dis (2017)

BET bromodomain inhibitors synergize with ATR inhibitors in melanoma

per Veppil Muralidharan, Somsundar, Osk Einarsdottir, Berglind, Bhadury, Joydeep, Lindberg, Mattias F, Wu, Jin, Campeau, Eric, Olofsson Bagge, Roger, Stierner, Ulrika, Ny, Lars, Nilsson, Lisa M, Nilsson, Jonas A
Publicat a Cell Death Dis (2017)

BET and HDAC inhibitors induce similar genes and biological effects and synergize to kill in Myc-induced murine lymphoma

per Bhadury, Joydeep, Nilsson, Lisa M., Veppil Muralidharan, Somsundar, Green, Lydia C., Li, Zhoulei, Gesner, Emily M., Hansen, Henrik C., Keller, Ulrich B., McLure, Kevin G., Nilsson, Jonas A.
Publicat 2014

Concomitant use of pembrolizumab and entinostat in adult patients with metastatic uveal melanoma (PEMDAC study): protocol for a multicenter phase II open label study

per Jespersen, Henrik, Olofsson Bagge, Roger, Ullenhag, Gustav, Carneiro, Ana, Helgadottir, Hildur, Ljuslinder, Ingrid, Levin, Max, All-Eriksson, Charlotta, Andersson, Bengt, Stierner, Ulrika, Nilsson, Lisa M., Nilsson, Jonas A., Ny, Lars
Publicat a BMC Cancer (2019)

Melanoma patient-derived xenografts accurately model the disease and develop fast enough to guide treatment decisions

per Einarsdottir, Berglind O., Bagge, Roger Olofsson, Bhadury, Joydeep, Jespersen, Henrik, Mattsson, Jan, Nilsson, Lisa M., Truvé, Katarina, López, Marcela Dávila, Naredi, Peter, Nilsson, Ola, Stierner, Ulrika, Ny, Lars, Nilsson, Jonas A.
Publicat a Oncotarget (2014)

Molecular profiling of driver events in metastatic uveal melanoma

per Karlsson, Joakim, Nilsson, Lisa M., Mitra, Suman, Alsén, Samuel, Shelke, Ganesh Vilas, Sah, Vasu R., Forsberg, Elin M. V., Stierner, Ulrika, All-Eriksson, Charlotta, Einarsdottir, Berglind, Jespersen, Henrik, Ny, Lars, Lindnér, Per, Larsson, Erik, Olofsson Bagge, Roger, Nilsson, Jonas A.
Publicat a Nat Commun (2020)

Mutational Signature and Transcriptomic Classification Analyses as the Decisive Diagnostic Tools for a Cancer of Unknown Primary

per Bagge, Roger Olofsson, Demir, Akif, Karlsson, Joakim, Alaei-Mahabadi, Babak, Einarsdottir, Berglind O., Jespersen, Henrik, Lindberg, Mattias F., Muth, Andreas, Nilsson, Lisa M., Persson, Marta, Svensson, Johanna B., Söderberg, Elin M.V., de Krijger, Ronald R., Nilsson, Ola, Larsson, Erik, Stenman, Göran, Nilsson, Jonas A.
Publicat a JCO Precis Oncol (2018)

A patient-derived xenograft pre-clinical trial reveals treatment responses and a resistance mechanism to karonudib in metastatic melanoma

per Einarsdottir, Berglind O., Karlsson, Joakim, Söderberg, Elin M. V., Lindberg, Mattias F., Funck-Brentano, Elisa, Jespersen, Henrik, Brynjolfsson, Siggeir F., Olofsson Bagge, Roger, Carstam, Louise, Scobie, Martin, Koolmeister, Tobias, Wallner, Olof, Stierner, Ulrika, Berglund, Ulrika Warpman, Ny, Lars, Nilsson, Lisa M., Larsson, Erik, Helleday, Thomas, Nilsson, Jonas A.
Publicat a Cell Death Dis (2018)

Correction: A patient-derived xenograft pre-clinical trial reveals treatment responses and a resistance mechanism to karonudib in metastatic melanoma

per Einarsdottir, Berglind O., Karlsson, Joakim, Söderberg, Elin M. V., Lindberg, Mattias F., Funck-Brentano, Elisa, Jespersen, Henrik, Brynjolfsson, Siggeir F., Bagge, Roger Olofsson, Carstam, Louise, Scobie, Martin, Koolmeister, Tobias, Wallner, Olof, Stierner, Ulrika, Berglund, Ulrika Warpman, Ny, Lars, Nilsson, Lisa M., Larsson, Erik, Helleday, Thomas, Nilsson, Jonas A.
Publicat a Cell Death Dis (2020)