Molecular profiling of driver events in metastatic uveal melanoma

Metastatic uveal melanoma is less well understood than its primary counterpart, has a distinct biology compared to skin melanoma, and lacks effective treatments. Here we genomically profile metastatic tumors and infiltrating lymphocytes. BAP1 alterations are overrepresented and found in 29/32 of cas...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Karlsson, Joakim, Nilsson, Lisa M., Mitra, Suman, Alsén, Samuel, Shelke, Ganesh Vilas, Sah, Vasu R., Forsberg, Elin M. V., Stierner, Ulrika, All-Eriksson, Charlotta, Einarsdottir, Berglind, Jespersen, Henrik, Ny, Lars, Lindnér, Per, Larsson, Erik, Olofsson Bagge, Roger, Nilsson, Jonas A.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171146/
https://ncbi.nlm.nih.gov/pubmed/32313009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15606-0
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