ERKing Trypanosoma: PCNA phosphorylation as novel target

od Nicolae, Claudia M., Moldovan, George-Lucian
Izdano u Cell Cycle (2016)

Genome-wide CRISPR synthetic lethality screen identifies a role for the ADP-ribosyltransferase PARP14 in DNA replication dynamics controlled by ATR

od Dhoonmoon, Ashna, Schleicher, Emily M, Clements, Kristen E, Nicolae, Claudia M, Moldovan, George-Lucian
Izdano u Nucleic Acids Res (2020)

PARP10 promotes cellular proliferation and tumorigenesis by alleviating replication stress

od Schleicher, Emily M, Galvan, Adri M, Imamura-Kawasawa, Yuka, Moldovan, George-Lucian, Nicolae, Claudia M
Izdano u Nucleic Acids Res (2018)

Loss of E2F7 confers resistance to poly-ADP-ribose polymerase (PARP) inhibitors in BRCA2-deficient cells

od Clements, Kristen E, Thakar, Tanay, Nicolae, Claudia M, Liang, Xinwen, Wang, Hong-Gang, Moldovan, George-Lucian
Izdano u Nucleic Acids Res (2018)

Ubiquitinated-PCNA protects replication forks from DNA2-mediated degradation by regulating Okazaki fragment maturation and chromatin assembly

od Thakar, Tanay, Leung, Wendy, Nicolae, Claudia M., Clements, Kristen E., Shen, Binghui, Bielinsky, Anja-Katrin, Moldovan, George-Lucian
Izdano u Nat Commun (2020)

The ADP-ribosyltransferase PARP10/ARTD10 Interacts with Proliferating Cell Nuclear Antigen (PCNA) and Is Required for DNA Damage Tolerance

od Nicolae, Claudia M., Aho, Erin R., Vlahos, Alexander H. S., Choe, Katherine N., De, Subhajyoti, Karras, Georgios I., Moldovan, George-Lucian
Izdano 2014

Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the resistance to multiple ATR inhibitors

od Schleicher, Emily M., Dhoonmoon, Ashna, Jackson, Lindsey M., Clements, Kristen E., Stump, Coryn L., Nicolae, Claudia M., Moldovan, George-Lucian
Izdano u PLoS Genet (2020)

PARI overexpression promotes genomic instability and pancreatic tumorigenesis

od O’Connor, Kevin W., Dejsuphong, Donniphat, Park, Eunmi, Nicolae, Claudia M., Kimmelman, Alec C., D’Andrea, Alan D., Moldovan, George-Lucian
Izdano 2013

A novel role for the mono-ADP-ribosyltransferase PARP14/ARTD8 in promoting homologous recombination and protecting against replication stress

od Nicolae, Claudia M., Aho, Erin R., Choe, Katherine N., Constantin, Daniel, Hu, He-Juan, Lee, Deokjae, Myung, Kyungjae, Moldovan, George-Lucian
Izdano u Nucleic Acids Res (2015)

Error-prone replication of a 5-formylcytosine-mediated DNA-peptide cross-link in human cells

od Naldiga, Spandana, Ji, Shaofei, Thomforde, Jenna, Nicolae, Claudia M., Lee, Marietta, Zhang, Zhongtao, Moldovan, George-Lucian, Tretyakova, Natalia Y., Basu, Ashis K.
Izdano u J Biol Chem (2019)

PARP10 deficiency manifests by infantile neurodegeneration and DNA repair defect

od Shahrour, Maher Awni, Nicolae, Claudia M., Edvardson, Simon, Ashhab, Motee, Galvan, Adri M., Constantin, Daniel, Abu-Libdeh, Bassam, Moldovan, George-Lucian, Elpeleg, Orly
Izdano u Neurogenetics (2016)

HUWE1 interacts with PCNA to alleviate replication stress

od Choe, Katherine N, Nicolae, Claudia M, Constantin, Daniel, Imamura Kawasawa, Yuka, Delgado‐Diaz, Maria Rocio, De, Subhajyoti, Freire, Raimundo, Smits, Veronique AJ, Moldovan, George‐Lucian
Izdano u EMBO Rep (2016)

Heterozygous RNF13 Gain-of-Function Variants Are Associated with Congenital Microcephaly, Epileptic Encephalopathy, Blindness, and Failure to Thrive

od Edvardson, Simon, Nicolae, Claudia M., Noh, Grace J., Burton, Jennifer E., Punzi, Giuseppe, Shaag, Avraham, Bischetsrieder, Jessica, De Grassi, Anna, Pierri, Ciro Leonardo, Elpeleg, Orly, Moldovan, George-Lucian
Izdano u Am J Hum Genet (2019)

FANCJ compensates for RAP80 deficiency and suppresses genomic instability induced by interstrand cross-links

od Awate, Sanket, Sommers, Joshua A, Datta, Arindam, Nayak, Sumeet, Bellani, Marina A, Yang, Olivia, Dunn, Christopher A, Nicolae, Claudia M, Moldovan, George-Lucian, Seidman, Michael M, Cantor, Sharon B, Brosh, Robert M
Izdano u Nucleic Acids Res (2020)

Identification of regulators of poly-ADP-ribose polymerase inhibitor response through complementary CRISPR knockout and activation screens

od Clements, Kristen E., Schleicher, Emily M., Thakar, Tanay, Hale, Anastasia, Dhoonmoon, Ashna, Tolman, Nathanial J., Sharma, Anchal, Liang, Xinwen, Imamura Kawasawa, Yuka, Nicolae, Claudia M., Wang, Hong-Gang, De, Subhajyoti, Moldovan, George-Lucian
Izdano u Nat Commun (2020)

STING promotes homeostasis via regulation of cell proliferation and chromosomal stability

od Ranoa, Diana Rose E., Widau, Ryan C., Mallon, Stephen, Parekh, Akash D., Nicolae, Claudia M., Huang, Xiaona, Bolt, Michael J., Arina, Ainhoa, Parry, Renate, Kron, Stephen J., Moldovan, George-Lucian, Khodarev, Nikolai N., Weichselbaum, Ralph R.
Izdano u Cancer Res (2018)

Heterozygous De Novo UBTF Gain-of-Function Variant Is Associated with Neurodegeneration in Childhood

od Edvardson, Simon, Nicolae, Claudia M., Agrawal, Pankaj B., Mignot, Cyril, Payne, Katelyn, Prasad, Asuri Narayan, Prasad, Chitra, Sadler, Laurie, Nava, Caroline, Mullen, Thomas E., Begtrup, Amber, Baskin, Berivan, Powis, Zöe, Shaag, Avraham, Keren, Boris, Moldovan, George-Lucian, Elpeleg, Orly
Izdano u Am J Hum Genet (2017)