PARP10 promotes cellular proliferation and tumorigenesis by alleviating replication stress

During carcinogenesis, cells are exposed to increased replication stress due to replication fork arrest at sites of DNA lesions and difficult to replicate genomic regions. Efficient fork restart and DNA repair are important for cancer cell proliferation. We previously showed that the ADP-ribosyltran...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Schleicher, Emily M, Galvan, Adri M, Imamura-Kawasawa, Yuka, Moldovan, George-Lucian, Nicolae, Claudia M
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2018
Предметы:
Genome Integrity, Repair and Replication
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158756/
https://ncbi.nlm.nih.gov/pubmed/30032250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky658
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