PARP10 promotes cellular proliferation and tumorigenesis by alleviating replication stress

During carcinogenesis, cells are exposed to increased replication stress due to replication fork arrest at sites of DNA lesions and difficult to replicate genomic regions. Efficient fork restart and DNA repair are important for cancer cell proliferation. We previously showed that the ADP-ribosyltran...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Schleicher, Emily M, Galvan, Adri M, Imamura-Kawasawa, Yuka, Moldovan, George-Lucian, Nicolae, Claudia M
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Genome Integrity, Repair and Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158756/
https://ncbi.nlm.nih.gov/pubmed/30032250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky658
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