HUWE1 interacts with PCNA to alleviate replication stress

Defects in DNA replication, DNA damage response, and DNA repair compromise genomic stability and promote cancer development. In particular, unrepaired DNA lesions can arrest the progression of the DNA replication machinery during S‐phase, causing replication stress, mutations, and DNA breaks. HUWE1...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Choe, Katherine N, Nicolae, Claudia M, Constantin, Daniel, Imamura Kawasawa, Yuka, Delgado‐Diaz, Maria Rocio, De, Subhajyoti, Freire, Raimundo, Smits, Veronique AJ, Moldovan, George‐Lucian
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278616/
https://ncbi.nlm.nih.gov/pubmed/27146073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201541685
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