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PARP10 promotes cellular proliferation and tumorigenesis by alleviating replication stress

During carcinogenesis, cells are exposed to increased replication stress due to replication fork arrest at sites of DNA lesions and difficult to replicate genomic regions. Efficient fork restart and DNA repair are important for cancer cell proliferation. We previously showed that the ADP-ribosyltran...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Schleicher, Emily M, Galvan, Adri M, Imamura-Kawasawa, Yuka, Moldovan, George-Lucian, Nicolae, Claudia M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158756/
https://ncbi.nlm.nih.gov/pubmed/30032250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky658
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