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Error-prone replication of a 5-formylcytosine-mediated DNA-peptide cross-link in human cells
DNA–protein cross-links can interfere with chromatin architecture, block DNA replication and transcription, and interfere with DNA repair. Here we synthesized a DNA 23-mer containing a site-specific DNA–peptide cross-link (DpC) by cross-linking an 11-mer peptide to the DNA epigenetic mark 5-formylcy...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6615699/ https://ncbi.nlm.nih.gov/pubmed/31138652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008879 |
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