Posttranslational regulation of the NKG2D ligand Mult1 in response to cell stress

Por Nice, Timothy J., Coscoy, Laurent, Raulet, David H.
Publicado em 2009

Interferon-λ: Immune Functions at Barrier Surfaces and Beyond

Por Lazear, Helen M., Nice, Timothy J., Diamond, Michael S.
Publicado no Immunity (2015)

Stress-regulated targeting of the NKG2D ligand Mult1 by a MARCH family E3 ligase

Por Nice, Timothy J., Deng, Weiwen, Coscoy, Laurent, Raulet, David H.
Publicado em 2010

The role of interferon in persistent viral infection: insights from murine norovirus

Por Nice, Timothy J., Robinson, Bridget A., Van Winkle, Jacob A.
Publicado no Trends Microbiol (2017)

A Single-Amino-Acid Change in Murine Norovirus NS1/2 Is Sufficient for Colonic Tropism and Persistence

Por Nice, Timothy J., Strong, David W., McCune, Broc T., Pohl, Calvin S., Virgin, Herbert W.
Publicado em 2013

Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity

Por Nice, Timothy J., Osborne, Lisa C., Tomov, Vesselin T., Artis, David, Wherry, E. John, Virgin, Herbert W.
Publicado no PLoS Pathog (2016)

Correction: Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity

Por Nice, Timothy J., Osborne, Lisa C., Tomov, Vesselin T., Artis, David, Wherry, E. John, Virgin, Herbert W.
Publicado no PLoS Pathog (2017)

Caspase-mediated cleavage of murine norovirus NS1/2 potentiates apoptosis and is required for persistent infection of intestinal epithelial cells

Por Robinson, Bridget A., Van Winkle, Jacob A., McCune, Broc T., Peters, A. Mack, Nice, Timothy J.
Publicado no PLoS Pathog (2019)

Murine Norovirus Protein NS1/2 Aspartate to Glutamate Mutation Sufficient for Persistence Reorients Side chain of Surface Exposed Tryptophan within a Novel Structured Domain

Por Borin, Brendan N., Tang, Wei, Nice, Timothy J., McCune, Broc T., Virgin, Herbert W., Krezel, Andrzej M.
Publicado em 2013

Expression of Ifnlr1 on Intestinal Epithelial Cells Is Critical to the Antiviral Effects of Interferon Lambda against Norovirus and Reovirus

Por Baldridge, Megan T., Lee, Sanghyun, Brown, Judy J., McAllister, Nicole, Urbanek, Kelly, Dermody, Terence S., Nice, Timothy J., Virgin, Herbert W.
Publicado no J Virol (2017)

Persistence of systemic murine norovirus is maintained by inflammatory recruitment of susceptible myeloid cells

Por Van Winkle, Jacob A., Robinson, Bridget A., Peters, A. Mack, Li, Lena, Nouboussi, Ruth V., Mack, Matthias, Nice, Timothy J.
Publicado no Cell Host Microbe (2018)

Interferon λ cures persistent murine norovirus infection in the absence of adaptive immunity

Por Nice, Timothy J., Baldridge, Megan T., McCune, Broc T., Norman, Jason M., Lazear, Helen M., Artyomov, Maxim, Diamond, Michael S., Virgin, Herbert W.
Publicado no Science (2014)

Commensal microbes and interferon-λ determine persistence of enteric murine norovirus infection

Por Baldridge, Megan T., Nice, Timothy J., McCune, Broc T., Yokoyama, Christine C., Kambal, Amal, Wheadon, Michael, Diamond, Michael S., Ivanova, Yulia, Artyomov, Maxim, Virgin, Herbert W.
Publicado no Science (2014)

Norovirus Cell Tropism is Determined by Combinatorial Action of a Viral Non-structural Protein and Host Cytokine

Por Lee, Sanghyun, Wilen, Craig B., Orvedahl, Anthony, McCune, Broc T., Kim, Ki-Wook, Orchard, Robert C., Peterson, Stefan T., Nice, Timothy J., Baldridge, Megan T., Virgin, Herbert W.
Publicado no Cell Host Microbe (2017)

Noroviruses Co-opt the Function of Host Proteins VAPA and VAPB for Replication via a Phenylalanine–Phenylalanine-Acidic-Tract-Motif Mimic in Nonstructural Viral Protein NS1/2

Por McCune, Broc T., Tang, Wei, Lu, Jia, Eaglesham, James B., Thorne, Lucy, Mayer, Anne E., Condiff, Emily, Nice, Timothy J., Goodfellow, Ian, Krezel, Andrzej M., Virgin, Herbert W.
Publicado no mBio (2017)

HOIL1 Is Essential for the Induction of Type I and III Interferons by MDA5 and Regulates Persistent Murine Norovirus Infection

Por MacDuff, Donna A., Baldridge, Megan T., Qaqish, Arwa M., Nice, Timothy J., Darbandi, Azad D., Hartley, Victoria L., Peterson, Stefan T., Miner, Jonathan J., Iwai, Kazuhiro, Virgin, Herbert W.
Publicado no J Virol (2018)

Differentiation and protective capacity of virus-specific CD8(+) T cells suggest murine norovirus persistence in an immune-privileged enteric niche

Por Tomov, Vesselin T., Palko, Olesya, Lau, Chi Wai, Pattekar, Ajinkya, Sun, Yuhang, Tacheva, Ralitza, Bengsch, Bertram, Manne, Sasikanth, Cosma, Gabriela L., Eisenlohr, Laurence, Nice, Timothy J., Virgin, Herbert W., Wherry, E. John
Publicado no Immunity (2017)

IFN-I and IL-22 mediate protective effects of intestinal viral infection

Por Neil, Jessica A, Matsuzawa-Ishimoto, Yu, Kernbauer-Hölzl, Elisabeth, Schuster, Samantha L, Sota, Stela, Venzon, Mericien, Dallari, Simone, Galvao Neto, Antonio, Hine, Ashley, Hudesman, David, Loke, P’ng, Nice, Timothy J, Cadwell, Ken
Publicado no Nat Microbiol (2019)

Type I Interferons link viral infection to enhanced epithelial turnover and repair

Por Sun, Lulu, Miyoshi, Hiroyuki, Origanti, Sofia, Nice, Timothy J., Barger, Alexandra C., Manieri, Nicholas A., Fogel, Leslie A., French, Anthony R., Piwnica-Worms, David, Piwnica-Worms, Helen, Virgin, Herbert W., Lenschow, Deborah J., Stappenbeck, Thaddeus S.
Publicado no Cell Host Microbe (2014)

A secreted viral non-structural protein determines intestinal norovirus pathogenesis

Por Lee, Sanghyun, Liu, Hejun, Wilen, Craig B., Sychev, Zoi E., Desai, Chandni, Hykes, Barry L., Orchard, Robert C., McCune, Broc T., Kim, Ki-Wook, Nice, Timothy J., Handley, Scott A., Baldridge, Megan T., Amarasinghe, Gaya K., Virgin, Herbert W.
Publicado no Cell Host Microbe (2019)