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A Single-Amino-Acid Change in Murine Norovirus NS1/2 Is Sufficient for Colonic Tropism and Persistence

Human norovirus (HuNoV) is the major cause of acute nonbacterial gastroenteritis worldwide but has no clear animal reservoir. HuNoV can persist after the resolution of symptoms, and this persistence may be essential for viral maintenance within the population. Many strains of the related murine noro...

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Detalhes bibliográficos
Main Authors: Nice, Timothy J., Strong, David W., McCune, Broc T., Pohl, Calvin S., Virgin, Herbert W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536416/
https://ncbi.nlm.nih.gov/pubmed/23077309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01864-12
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