Interferon λ cures persistent murine norovirus infection in the absence of adaptive immunity

Norovirus gastroenteritis is a major public health burden worldwide. Although fecal shedding is important for transmission of enteric viruses, little is known about the immune factors that restrict persistent enteric infection. We report here that while the cytokines interferon-α (IFN-α) and IFN-β p...

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Udgivet i:Science
Main Authors: Nice, Timothy J., Baldridge, Megan T., McCune, Broc T., Norman, Jason M., Lazear, Helen M., Artyomov, Maxim, Diamond, Michael S., Virgin, Herbert W.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398891/
https://ncbi.nlm.nih.gov/pubmed/25431489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1258100
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