RLIP76 (RalBP1): The first piece of the structural puzzle

Por Mott, Helen R, Owen, Darerca
Publicado em 2010

Class IA PI3K regulatory subunits: p110-independent roles and structures

Por Fox, Millie, Mott, Helen R., Owen, Darerca
Publicado no Biochem Soc Trans (2020)

Activation of STAT transcription factors by the Rho-family GTPases

Por Corry, Jessica, Mott, Helen R., Owen, Darerca
Publicado no Biochem Soc Trans (2020)

The structure and function of protein kinase C-related kinases (PRKs)

Por Sophocleous, Georgios, Owen, Darerca, Mott, Helen R.
Publicado no Biochem Soc Trans (2021)

Cdc42 in actin dynamics: An ordered pathway governed by complex equilibria and directional effector handover

Por Watson, Joanna R., Owen, Darerca, Mott, Helen R.
Publicado no Small GTPases (2016)

(1)H, (15)N and (13)C resonance assignments of the HR1c domain of PRK1, a protein kinase C-related kinase

Por Sophocleous, Georgios, Wood, George, Owen, Darerca, Mott, Helen R.
Publicado no Biomol NMR Assign (2020)

(1)H, (13)C and (15)N resonance assignments of the Cdc42-binding domain of TOCA1

Por Watson, Joanna R., Nietlispach, Daniel, Owen, Darerca, Mott, Helen R.
Publicado no Biomol NMR Assign (2016)

Erratum to: (1)H, (13)C and (15)N resonance assignments of the Cdc42-binding domain of TOCA1

Por Watson, Joanna R., Nietlispach, Daniel, Owen, Darerca, Mott, Helen R.
Publicado no Biomol NMR Assign (2016)

NMR resonance assignments for the active and inactive conformations of the small G protein RalA

Por Shafiq, Arooj, Campbell, Louise J., Owen, Darerca, Mott, Helen R.
Publicado no Biomol NMR Assign (2020)

Intrinsically disordered proteins and membranes: a marriage of convenience for cell signalling?

Por Cornish, Jasmine, Chamberlain, Samuel G., Owen, Darerca, Mott, Helen R.
Publicado no Biochem Soc Trans (2020)

A dock and coalesce mechanism driven by hydrophobic interactions governs Cdc42 binding with its effector protein ACK

Por Tetley, George J. N., Mott, Helen R., Cooley, R. Neil, Owen, Darerca
Publicado no J Biol Chem (2017)

Structure determination of the seven-helical transmembrane receptor sensory rhodopsin II by solution NMR spectroscopy

Por Gautier, Antoine, Mott, Helen R., Bostock, Mark J., Kirkpatrick, John P., Nietlispach, Daniel
Publicado em 2010

The Structure of the RLIP76 RhoGAP-Ral Binding Domain Dyad: Fixed Position of the Domains Leads to Dual Engagement of Small G Proteins at the Membrane

Por Rajasekar, Karthik V., Campbell, Louise J., Nietlispach, Daniel, Owen, Darerca, Mott, Helen R.
Publicado em 2013

Bond swapping from a charge cloud allows flexible coordination of upstream signals through WASP: Multiple regulatory roles for the WASP basic region

Por Tetley, George J. N., Szeto, Aydan, Fountain, Adam J., Mott, Helen R., Owen, Darerca
Publicado no J Biol Chem (2018)

Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases

Por Hurd, Catherine A., Brear, Paul, Revell, Jefferson, Ross, Sarah, Mott, Helen R., Owen, Darerca
Publicado no J Biol Chem (2020)

Integral membrane protein structure determination using pseudocontact shifts

Por Crick, Duncan J., Wang, Jue X., Graham, Bim, Swarbrick, James D., Mott, Helen R., Nietlispach, Daniel
Publicado no J Biomol NMR (2015)

Investigation of the Interaction between Cdc42 and Its Effector TOCA1: HANDOVER OF Cdc42 TO THE ACTIN REGULATOR N-WASP IS FACILITATED BY DIFFERENTIAL BINDING AFFINITIES

Por Watson, Joanna R., Fox, Helen M., Nietlispach, Daniel, Gallop, Jennifer L., Owen, Darerca, Mott, Helen R.
Publicado no J Biol Chem (2016)

The RalB-RLIP76 (RalBP1) complex reveals a novel mode of Ral-effector interaction

Por Fenwick, R. Brynmor, Campbell, Louise J., Rajasekar, Karthik, Prasannan, Sunil, Nietlispach, Daniel, Camonis, Jacques, Owen, Darerca, Mott, Helen R.
Publicado em 2010

Inhibition of Ral GTPases Using a Stapled Peptide Approach

Por Thomas, Jemima C., Cooper, Jonathan M., Clayton, Natasha S., Wang, Chensu, White, Michael A., Abell, Chris, Owen, Darerca, Mott, Helen R.
Publicado no J Biol Chem (2016)

The discovery and maturation of peptide biologics targeting the small G-protein Cdc42: A bioblockade for Ras-driven signaling

Por Tetley, George J. N., Murphy, Natasha P., Bonetto, Stephane, Ivanova-Berndt, Gabriela, Revell, Jefferson, Mott, Helen R., Cooley, R. Neil, Owen, Darerca
Publicado no J Biol Chem (2020)