JAK2(V617F) Drives Mcl-1 Expression and Sensitizes Hematologic Cell Lines to Dual Inhibition of JAK2 and Bcl-xL

Por Guo, Jun, Roberts, Lisa, Chen, Zhui, Merta, Philip J., Glaser, Keith B., Shah, O. Jameel
Publicado no PLoS One (2015)

Novel Approach to Mapping of Resistance Mutations in Whole Genomes by Using Restriction Enzyme Modulation of Transformation Efficiency

Por Lerner, Claude G., Kakavas, Stephan J., Wagner, Christian, Chang, Richard T., Merta, Philip J., Ruan, Xiaoan, Metzger, Randy E., Beutel, Bruce A.
Publicado em 2005

Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195

Por Tong, Yunsong, Stewart, Kent D., Florjancic, Alan S., Harlan, John E., Merta, Philip J., Przytulinska, Magdalena, Soni, Nirupama, Swinger, Kerren K., Zhu, Haizhong, Johnson, Eric F., Shoemaker, Alexander R., Penning, Thomas D.
Publicado em 2013

Pyrimidine-Based Tricyclic Molecules as Potent and Orally Efficacious Inhibitors of Wee1 Kinase

Por Tong, Yunsong, Torrent, Maricel, Florjancic, Alan S., Bromberg, Kenneth D., Buchanan, Fritz G., Ferguson, Debra C., Johnson, Eric F., Lasko, Loren M., Maag, David, Merta, Philip J., Olson, Amanda M., Osterling, Donald J., Soni, Nirupama, Shoemaker, Alexander R., Penning, Thomas D.
Publicado no ACS Med Chem Lett (2014)

Tricyclic Covalent Inhibitors Selectively Target Jak3 through an Active Site Thiol

Por Goedken, Eric R., Argiriadi, Maria A., Banach, David L., Fiamengo, Bryan A., Foley, Sage E., Frank, Kristine E., George, Jonathan S., Harris, Christopher M., Hobson, Adrian D., Ihle, David C., Marcotte, Douglas, Merta, Philip J., Michalak, Mark E., Murdock, Sara E., Tomlinson, Medha J., Voss, Jeffrey W.
Publicado no J Biol Chem (2015)

Potent and Selective Inhibitors of CDPK1 from T. gondii and C. parvum Based on a 5-Aminopyrazole-4-carboxamide Scaffold

Por Zhang, Zhongsheng, Ojo, Kayode K., Vidadala, RamaSubbaRao, Huang, Wenlin, Geiger, Jennifer A., Scheele, Suzanne, Choi, Ryan, Reid, Molly C., Keyloun, Katelyn R., Rivas, Kasey, Kallur Siddaramaiah, Latha, Comess, Kenneth M., Robinson, Kenneth P., Merta, Philip J., Kifle, Lemma, Hol, Wim G. J., Parsons, Marilyn, Merritt, Ethan A., Maly, Dustin J., Verlinde, Christophe L. M. J., Van Voorhis, Wesley C., Fan, Erkang
Publicado em 2013

Novel Antibacterial Class

Por Dandliker, Peter J., Pratt, Steve D., Nilius, Angela M., Black-Schaefer, Candace, Ruan, Xiaoan, Towne, Danli L., Clark, Richard F., Englund, Erika E., Wagner, Rolf, Weitzberg, Moshe, Chovan, Linda E., Hickman, Robert K., Daly, Melissa M., Kakavas, Stephan, Zhong, Ping, Cao, Zhensheng, David, Caroline A., Xuei, Xiaoling, Lerner, Claude G., Soni, Niru B., Bui, Mai, Shen, Linus L., Cai, Yingna, Merta, Philip J., Saiki, Anne Y. C., Beutel, Bruce A.
Publicado em 2003