On-column ligand exchange for structure-based drug design: a case study with human 11β-hydroxysteroid dehydrogenase type 1

Por Qin, Wenying, Judge, Russell A., Longenecker, Kenton L., Solomon, Larry R., Harlan, John E.
Publicado em 2012

The BH3 Domain of Bcl-x(S) Is Required for Inhibition of the Antiapoptotic Function of Bcl-x(L)

Por Chang, Brian S., Kelekar, Ameeta, Harris, Marian H., Harlan, John E., Fesik, Stephen W., Thompson, Craig B.
Publicado em 1999

Ligand association rates to the inner-variable-domain of a dual-variable-domain immunoglobulin are significantly impacted by linker design

Por DiGiammarino, Enrico L, Harlan, John E, Walter, Karl A, Ladror, Uri S, Edalji, Rohinton P, Hutchins, Charles W, Lake, Marc R, Greischar, Amy J, Liu, Junjian, Ghayur, Tariq, Jakob, Clarissa G
Publicado em 2011

Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195

Por Tong, Yunsong, Stewart, Kent D., Florjancic, Alan S., Harlan, John E., Merta, Philip J., Przytulinska, Magdalena, Soni, Nirupama, Swinger, Kerren K., Zhu, Haizhong, Johnson, Eric F., Shoemaker, Alexander R., Penning, Thomas D.
Publicado em 2013

Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure

Por Longenecker, Kenton L., Stamper, Geoffrey F., Hajduk, Philip J., Fry, Elizabeth H., Jakob, Clarissa G., Harlan, John E., Edalji, Rohinton, Bartley, Diane M., Walter, Karl A., Solomon, Larry R., Holzman, Thomas F., Gu, Yu Gui, Lerner, Claude G., Beutel, Bruce A., Stoll, Vincent S.
Publicado em 2005