On-column ligand exchange for structure-based drug design: a case study with human 11β-hydroxysteroid dehydrogenase type 1

af Qin, Wenying, Judge, Russell A., Longenecker, Kenton L., Solomon, Larry R., Harlan, John E.
Udgivet 2012

The BH3 Domain of Bcl-x(S) Is Required for Inhibition of the Antiapoptotic Function of Bcl-x(L)

af Chang, Brian S., Kelekar, Ameeta, Harris, Marian H., Harlan, John E., Fesik, Stephen W., Thompson, Craig B.
Udgivet 1999

Ligand association rates to the inner-variable-domain of a dual-variable-domain immunoglobulin are significantly impacted by linker design

af DiGiammarino, Enrico L, Harlan, John E, Walter, Karl A, Ladror, Uri S, Edalji, Rohinton P, Hutchins, Charles W, Lake, Marc R, Greischar, Amy J, Liu, Junjian, Ghayur, Tariq, Jakob, Clarissa G
Udgivet 2011

Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195

af Tong, Yunsong, Stewart, Kent D., Florjancic, Alan S., Harlan, John E., Merta, Philip J., Przytulinska, Magdalena, Soni, Nirupama, Swinger, Kerren K., Zhu, Haizhong, Johnson, Eric F., Shoemaker, Alexander R., Penning, Thomas D.
Udgivet 2013

Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure

af Longenecker, Kenton L., Stamper, Geoffrey F., Hajduk, Philip J., Fry, Elizabeth H., Jakob, Clarissa G., Harlan, John E., Edalji, Rohinton, Bartley, Diane M., Walter, Karl A., Solomon, Larry R., Holzman, Thomas F., Gu, Yu Gui, Lerner, Claude G., Beutel, Bruce A., Stoll, Vincent S.
Udgivet 2005