Resultados da pesquisa por Autor

1

New Approaches for the Discovery of Pharmacologically-Active Natural Compounds

New Approaches for the Discovery of Pharmacologically-Active Natural Compounds

Por Medina-Franco, José L.
Publicado em 2019

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2

Computer-guided discovery of epigenetics drugs: molecular modeling and identification of inhibitors of DNMT1

Computer-guided discovery of epigenetics drugs: molecular modeling and identification of inhibitors of DNMT1

Por Yoo, Jakyung, Medina-Franco, José L
Publicado em 2012

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3

On the validity versus utility of activity landscapes: are all activity cliffs statistically significant?

On the validity versus utility of activity landscapes: are all activity cliffs statistically significant?

Por Guha, Rajarshi, Medina-Franco, José L
Publicado em 2014

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4

ChemMaps: Towards an approach for visualizing the chemical space based on adaptive satellite compounds

ChemMaps: Towards an approach for visualizing the chemical space based on adaptive satellite compounds

Por Naveja, J. Jesús, Medina-Franco, José L.
Publicado no F1000Res (2017)

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5

Molecular Modeling Studies of the Novel Inhibitors of DNA Methyltransferases SGI-1027 and CBC12: Implications for the Mechanism of Inhibition of DNMTs

Molecular Modeling Studies of the Novel Inhibitors of DNA Methyltransferases SGI-1027 and CBC12: Implications for the Mechanism of Inhibition of DNMTs

Por Yoo, Jakyung, Choi, Sun, Medina-Franco, José L.
Publicado em 2013

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6

Rationalization of Activity Cliffs of a Sulfonamide Inhibitor of DNA Methyltransferases with Induced-Fit Docking

Rationalization of Activity Cliffs of a Sulfonamide Inhibitor of DNA Methyltransferases with Induced-Fit Docking

Por Medina-Franco, José L., Méndez-Lucio, Oscar, Yoo, Jakyung
Publicado em 2014

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7

Shifting from the single- to the multitarget paradigm in drug discovery

Shifting from the single- to the multitarget paradigm in drug discovery

Por Medina-Franco, José L., Giulianotti, Marc A., Welmaker, Gregory S., Houghten, Richard A.
Publicado em 2013

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8

Molecular Modeling of Inhibitors of Human DNA Methyltransferase with a Crystal Structure: Discovery of a Novel DNMT1 Inhibitor

Molecular Modeling of Inhibitors of Human DNA Methyltransferase with a Crystal Structure: Discovery of a Novel DNMT1 Inhibitor

Por Yoo, Jakyung, Kim, Joo Hee, Robertson, Keith D., Medina-Franco, José L.
Publicado em 2012

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9

Chemoinformatic Analysis of GRAS (Generally Recognized as Safe) Flavor Chemicals and Natural Products

Chemoinformatic Analysis of GRAS (Generally Recognized as Safe) Flavor Chemicals and Natural Products

Por Medina-Franco, José L., Martínez-Mayorga, Karina, Peppard, Terry L., Del Rio, Alberto
Publicado em 2012

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10

Conditional Probabilistic Analysis for Prediction of the Activity Landscape and Relative Compound Activities

Conditional Probabilistic Analysis for Prediction of the Activity Landscape and Relative Compound Activities

Por Santos, Radleigh G., Giulianotti, Marc A., Houghten, Richard A., Medina-Franco, José L.
Publicado em 2013

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11

Chemoinformatic Analysis of Combinatorial Libraries, Drugs, Natural Products and Molecular Libraries Small Molecule Repository

Chemoinformatic Analysis of Combinatorial Libraries, Drugs, Natural Products and Molecular Libraries Small Molecule Repository

Por Singh, Narender, Guha, Rajarshi, Giulianotti, Marc, Pinilla, Clemencia, Houghten, Richard, Medina-Franco, Jose L.
Publicado em 2009

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12

Consensus Diversity Plots: a global diversity analysis of chemical libraries

Consensus Diversity Plots: a global diversity analysis of chemical libraries

Por González-Medina, Mariana, Prieto-Martínez, Fernando D., Owen, John R., Medina-Franco, José L.
Publicado no J Cheminform (2016)

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13

A large scale classification of molecular fingerprints for the chemical space representation and SAR analysis

A large scale classification of molecular fingerprints for the chemical space representation and SAR analysis

Por López-Vallejo, Fabian, Waddell, Jacob, Yongye, Austin B, Houghten, Richard A, Medina-Franco, José L
Publicado em 2012

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14

Database fingerprint (DFP): an approach to represent molecular databases

Database fingerprint (DFP): an approach to represent molecular databases

Por Fernández-de Gortari, Eli, García-Jacas, César R., Martinez-Mayorga, Karina, Medina-Franco, José L.
Publicado no J Cheminform (2017)

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15

Activity-difference maps and consensus similarity measure characterize structure-activity relationships

Activity-difference maps and consensus similarity measure characterize structure-activity relationships

Por Medina-Franco, José L, Yongye, Austin B, Pérez-Villanueva, Jaime, Houghten, Richard A, Martínez-Mayorga, Karina
Publicado em 2012

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16

The prince and the pauper. A tale of anticancer targeted agents

The prince and the pauper. A tale of anticancer targeted agents

Por Dueñas-González, Alfonso, García-López, Patricia, Herrera, Luis Alonso, Medina-Franco, Jose Luis, González-Fierro, Aurora, Candelaria, Myrna
Publicado em 2008

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17

Effects of cyclic lipodepsipeptide structural modulation on stability, antibacterial activity and human cell toxicity

Effects of cyclic lipodepsipeptide structural modulation on stability, antibacterial activity and human cell toxicity

Por Bionda, Nina, Stawikowski, Maciej, Stawikowska, Roma, Cudic, Maré, López-Vallejo, Fabian, Treitl, Daniela, Medina-Franco, José, Cudic, Predrag
Publicado em 2012

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18

Increased Diversity of Libraries from Libraries: Chemoinformatic Analysis of Bis-Diazacyclic Libraries

Increased Diversity of Libraries from Libraries: Chemoinformatic Analysis of Bis-Diazacyclic Libraries

Por López-Vallejo, Fabian, Nefzi, Adel, Bender, Andreas, Owen, John R., Nabney, Ian T., Houghten, Richard A., Medina-Franco, Jose L.
Publicado em 2011

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19

Statistical correlation of nonconservative substitutions of HIV gp41 variable amino acid residues with the R5X4 HIV-1 phenotype

Statistical correlation of nonconservative substitutions of HIV gp41 variable amino acid residues with the R5X4 HIV-1 phenotype

Por Pacheco-Martínez, Elena, Figueroa-Medina, Evangelina, Villarreal, Carlos, Cocho, Germinal, Medina-Franco, José L., Méndez-Lucio, Oscar, Huerta, Leonor
Publicado no Virol J (2016)

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20

Resveratrol-salicylate derivatives as selective DNMT3 inhibitors and anticancer agents

Resveratrol-salicylate derivatives as selective DNMT3 inhibitors and anticancer agents

Por Aldawsari, Fahad S., Aguayo-Ortiz, Rodrigo, Kapilashrami, Kanishk, Yoo, Jakyung, Luo, Minkui, Medina-Franco, José L., Velázquez-Martínez, Carlos A.
Publicado no J Enzyme Inhib Med Chem (2015)

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