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Increased Diversity of Libraries from Libraries: Chemoinformatic Analysis of Bis-Diazacyclic Libraries

Combinatorial libraries continue to play a key role in drug discovery. To increase structural diversity, several experimental methods have been developed. However, limited efforts have been performed so far to quantify the diversity of the broadly used diversity-oriented synthetic (DOS) libraries. H...

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Detalhes bibliográficos
Main Authors: López-Vallejo, Fabian, Nefzi, Adel, Bender, Andreas, Owen, John R., Nabney, Ian T., Houghten, Richard A., Medina-Franco, Jose L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077462/
https://ncbi.nlm.nih.gov/pubmed/21294850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2011.01100.x
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