Virtual Screening Approaches towards the Discovery of Toll-Like Receptor Modulators

Por Pérez-Regidor, Lucía, Zarioh, Malik, Ortega, Laura, Martín-Santamaría, Sonsoles
Publicado no Int J Mol Sci (2016)

Insights into the key determinants of membrane protein topology enable the identification of new monotopic folds

Por Entova, Sonya, Billod, Jean-Marc, Swiecicki, Jean-Marie, Martín-Santamaría, Sonsoles, Imperiali, Barbara
Publicado no eLife (2018)

Molecular Basis of the Functional differences between soluble human vs. murine MD-2: Role of Val-135 in transfer of LPS from CD14 to MD-2()

Por Vašl, Jožica, Oblak, Alja, Peternelj, Tina T., Klett, Javier, Martín-Santamaría, Sonsoles, Gioannini, Theresa L., Weiss, Jerrold P., Jerala, Roman
Publicado no J Immunol (2016)

Potential anti-inflammatory, anti-adhesive, anti/estrogenic, and angiotensin-converting enzyme inhibitory activities of anthocyanins and their gut metabolites

Por Hidalgo, Maria, Martin-Santamaria, Sonsoles, Recio, Isidra, Sanchez-Moreno, Concepcion, de Pascual-Teresa, Beatriz, Rimbach, Gerald, de Pascual-Teresa, Sonia
Publicado em 2012

Antibiotic Capture by Bacterial Lipocalins Uncovers an Extracellular Mechanism of Intrinsic Antibiotic Resistance

Por El-Halfawy, Omar M., Klett, Javier, Ingram, Rebecca J., Loutet, Slade A., Murphy, Michael E. P., Martín-Santamaría, Sonsoles, Valvano, Miguel A.
Publicado no mBio (2017)

Modulation of CD14 and TLR4.MD-2 activities by a synthetic lipid A mimetic

Por Cighetti, Roberto, Ciaramelli, Carlotta, Sestito, Stefania Enza, Zanoni, Ivan, Kubik, Łukasz, Ardá-Freire, Ana, Calabrese, Valentina, Granucci, Francesca, Jerala, Roman, Martín-Santamaría, Sonsoles, Jiménez-Barbero, Jesus, Peri, Francesco
Publicado em 2013

Structural aspects of binding of α-linked digalactosides to human galectin-1

Por Miller, Michelle C, Ribeiro, João P, Roldós, Virginia, Martín-Santamaría, Sonsoles, Cañada, F Javier, Nesmelova, Irina A, André, Sabine, Pang, Mabel, Klyosov, Anatole A, Baum, Linda G, Jiménez-Barbero, Jesús, Gabius, Hans-Joachim, Mayo, Kevin H
Publicado em 2011

Activation of Human Toll-like Receptor 4 (TLR4)·Myeloid Differentiation Factor 2 (MD-2) by Hypoacylated Lipopolysaccharide from a Clinical Isolate of Burkholderia cenocepacia

Por Di Lorenzo, Flaviana, Kubik, Łukasz, Oblak, Alja, Lorè, Nicola Ivan, Cigana, Cristina, Lanzetta, Rosa, Parrilli, Michelangelo, Hamad, Mohamad A., De Soyza, Anthony, Silipo, Alba, Jerala, Roman, Bragonzi, Alessandra, Valvano, Miguel A., Martín-Santamaría, Sonsoles, Molinaro, Antonio
Publicado no J Biol Chem (2015)

Antagonistic Pleiotropy in the Bifunctional Surface Protein FadL (OmpP1) during Adaptation of Haemophilus influenzae to Chronic Lung Infection Associated with Chronic Obstructive P...

Por Moleres, Javier, Fernández-Calvet, Ariadna, Ehrlich, Rachel L., Martí, Sara, Pérez-Regidor, Lucía, Euba, Begoña, Rodríguez-Arce, Irene, Balashov, Sergey, Cuevas, Ester, Liñares, Josefina, Ardanuy, Carmen, Martín-Santamaría, Sonsoles, Ehrlich, Garth D., Mell, Joshua Chang, Garmendia, Junkal
Publicado no mBio (2018)

Bradyrhizobium Lipid A: Immunological Properties and Molecular Basis of Its Binding to the Myeloid Differentiation Protein-2/Toll-Like Receptor 4 Complex

Por Lembo-Fazio, Luigi, Billod, Jean-Marc, Di Lorenzo, Flaviana, Paciello, Ida, Pallach, Mateusz, Vaz-Francisco, Sara, Holgado, Aurora, Beyaert, Rudi, Fresno, Manuel, Shimoyama, Atsushi, Lanzetta, Rosa, Fukase, Koichi, Gully, Djamel, Giraud, Eric, Martín-Santamaría, Sonsoles, Bernardini, Maria-Lina, Silipo, Alba
Publicado no Front Immunol (2018)