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Insights into the key determinants of membrane protein topology enable the identification of new monotopic folds
Monotopic membrane proteins integrate into the lipid bilayer via reentrant hydrophobic domains that enter and exit on a single face of the membrane. Whereas many membrane-spanning proteins have been structurally characterized and transmembrane topologies can be predicted computationally, relatively...
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| Gepubliceerd in: | eLife |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
eLife Sciences Publications, Ltd
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6133551/ https://ncbi.nlm.nih.gov/pubmed/30168796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40889 |
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