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Molecular Basis of the Functional differences between soluble human vs. murine MD-2: Role of Val-135 in transfer of LPS from CD14 to MD-2()
Myeloid differentiation factor (MD-2) is an extracellular protein, associated with the ectodomain of Toll-like receptor 4 (TLR4), that plays a critical role in the recognition of bacterial lipopolysaccharide (LPS). Despite high overall structural and functional similarity, human (h) and murine (m) M...
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| Publicat a: | J Immunol |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5348922/ https://ncbi.nlm.nih.gov/pubmed/26826249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502074 |
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