Structural aspects of binding of α-linked digalactosides to human galectin-1

By definition, adhesion/growth-regulatory galectins are known for their ability to bind β-galactosides such as Galβ(1 → 4)Glc (lactose). Indications for affinity of human galectin-1 to α-linked digalactosides pose questions on the interaction profile with such bound ligands and selection of the gala...

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Detalhes bibliográficos
Main Authors: Miller, Michelle C, Ribeiro, João P, Roldós, Virginia, Martín-Santamaría, Sonsoles, Cañada, F Javier, Nesmelova, Irina A, André, Sabine, Pang, Mabel, Klyosov, Anatole A, Baum, Linda G, Jiménez-Barbero, Jesús, Gabius, Hans-Joachim, Mayo, Kevin H
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219418/
https://ncbi.nlm.nih.gov/pubmed/21712397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwr083
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