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The α-galactomannan Davanat binds galectin-1 at a site different from the conventional galectin carbohydrate binding domain

Galectins are a sub-family of lectins, defined by their highly conserved β-sandwich structures and ability to bind to β-galactosides, like Gal β1-4 Glc (lactose). Here, we used (15)N-(1)H HSQC and pulse field gradient (PFG) NMR spectroscopy to demonstrate that galectin-1 (gal-1) binds to the relativ...

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Autores principales: Miller, Michelle C, Klyosov, Anatole, Mayo, Kevin H
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720280/
https://ncbi.nlm.nih.gov/pubmed/19541770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwp084
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