Targeting Dendritic Cells in vivo for Cancer Therapy

Por Caminschi, Irina, Maraskovsky, Eugene, Heath, William Ross
Publicado em 2012

Dendritic Cell Development in Culture from Thymic Precursor Cells in the Absence of Granulocyte/Macrophage Colony-stimulating Factor

Por Saunders, Dolores, Lucas, Karen, Ismaili, Jamila, Wu, Li, Maraskovsky, Eugene, Dunn, Ashley, Shortman, Ken
Publicado em 1996

Therapeutic ISCOMATRIX™ adjuvant vaccine elicits effective anti-tumor immunity in the TRAMP-C1 mouse model of prostate cancer

Por Barr, Adele M., Silva, Anabel, Prato, Sandro, Belz, Gabrielle T., Maraskovsky, Eugene, Baz Morelli, Adriana
Publicado no Cancer Immunol Immunother (2020)

Interleukin (Il)-4 Is a Major Regulatory Cytokine Governing Bioactive IL-12 Production by Mouse and Human Dendritic Cells

Por Hochrein, Hubertus, O'Keeffe, Meredith, Luft, Thomas, Vandenabeele, Stéphane, Grumont, Raelene J., Maraskovsky, Eugene, Shortman, Ken
Publicado em 2000

Machine learning applied to whole‐blood RNA‐sequencing data uncovers distinct subsets of patients with systemic lupus erythematosus

Por Figgett, William A, Monaghan, Katherine, Ng, Milica, Alhamdoosh, Monther, Maraskovsky, Eugene, Wilson, Nicholas J, Hoi, Alberta Y, Morand, Eric F, Mackay, Fabienne
Publicado no Clin Transl Immunology (2019)

A potential association between IL‐3 and type I and III interferons in systemic lupus erythematosus

Por Oon, Shereen, Monaghan, Katherine, Ng, Milica, Hoi, Alberta, Morand, Eric, Vairo, Gino, Maraskovsky, Eugene, Nash, Andrew D, Wicks, Ian P, Wilson, Nicholas J
Publicado no Clin Transl Immunology (2019)

A cytotoxic anti-IL-3Rα antibody targets key cells and cytokines implicated in systemic lupus erythematosus

Por Oon, Shereen, Huynh, Huy, Tai, Tsin Yee, Ng, Milica, Monaghan, Katherine, Biondo, Mark, Vairo, Gino, Maraskovsky, Eugene, Nash, Andrew D., Wicks, Ian P., Wilson, Nicholas J.
Publicado no JCI Insight (2016)

Peptides identified on monocyte-derived dendritic cells: a marker for clinical immunogenicity to FVIII products

Por Jankowski, Wojciech, Park, Yara, McGill, Joseph, Maraskovsky, Eugene, Hofmann, Marco, Diego, Vincent P., Luu, Bernadette W., Howard, Tom E., Kellerman, Roberta, Key, Nigel S., Sauna, Zuben E.
Publicado no Blood Adv (2019)

A Novel Cellular Pathway of Antigen Presentation and CD4 T Cell Activation in vivo

Por Scales, Hannah E., Meehan, Gavin R., Hayes, Alan J., Benson, Robert A., Watson, Emma, Walters, Anne, Tomura, Michio, Maraskovsky, Eugene, Garside, Paul, Baz Morelli, Adriana, Brewer, James M.
Publicado no Front Immunol (2018)

Therapeutic Effect of IVIG on Inflammatory Arthritis in Mice Is Dependent on the Fc Portion and Independent of Sialylation or Basophils

Por Campbell, Ian K., Miescher, Sylvia, Branch, Donald R., Mott, Patrick J., Lazarus, Alan H., Han, Dongji, Maraskovsky, Eugene, Zuercher, Adrian W., Neschadim, Anton, Leontyev, Danila, McKenzie, Brent S., Käsermann, Fabian
Publicado em 2014

ISCOMATRIX Adjuvant Combines Immune Activation with Antigen Delivery to Dendritic Cells In Vivo Leading to Effective Cross-Priming of CD8(+) T Cells

Por Duewell, Peter, Kisser, Ulrich, Heckelsmiller, Klaus, Hoves, Sabine, Stoitzner, Patrizia, Koernig, Sandra, Morelli, Adriana B., Clausen, Björn E., Dauer, Marc, Eigler, Andreas, Anz, David, Bourquin, Carole, Maraskovsky, Eugene, Endres, Stefan, Schnurr, Max
Publicado no J Immunol (2011)

Complementary Signaling through flt3 and Interleukin-7 Receptor α Is Indispensable for Fetal and Adult B Cell Genesis

Por Sitnicka, Ewa, Brakebusch, Cord, Martensson, Inga-Lill, Svensson, Marcus, Agace, William W., Sigvardsson, Mikael, Buza-Vidas, Natalija, Bryder, David, M.Cilio, Corrado, Ahlenius, Henrik, Maraskovsky, Eugene, Peschon, Jacques J., Jacobsen, Sten Eirik W.
Publicado em 2003

ISCOMATRIX vaccines mediate CD8(+) T-cell cross-priming by a MyD88-dependent signaling pathway

Por Wilson, Nicholas S, Yang, Becky, Morelli, Adriana Baz, Koernig, Sandra, Yang, Annie, Loeser, Stefanie, Airey, Denise, Provan, Larissa, Hass, Phil, Braley, Hal, Couto, Suzana, Drane, Debbie, Boyle, Jeff, Belz, Gabrielle T, Ashkenazi, Avi, Maraskovsky, Eugene
Publicado em 2012

Optimal effector functions in human natural killer cells rely upon autocrine bone morphogenetic protein signaling

Por Robson, Neil C., Hidalgo, Laura, Mc Alpine, Tristan, Wei, Heng, Martínez, Víctor G., Entrena, Ana, Melen, Gustavo J, MacDonald, Andrew S., Phythian-Adams, Alexander, Sacedón, Rosa, Maraskovsky, Eugene, Cebon, Jonathan, Ramírez, Manuel, Vicente, Angeles, Varas, Alberto
Publicado em 2014

The dominant role of CD8(+) dendritic cells in cross-presentation is not dictated by antigen capture

Por Schnorrer, Petra, Behrens, Georg M. N., Wilson, Nicholas S., Pooley, Joanne L., Smith, Christopher M., El-Sukkari, Dima, Davey, Gayle, Kupresanin, Fiona, Li, Ming, Maraskovsky, Eugene, Belz, Gabrielle T., Carbone, Francis R., Shortman, Ken, Heath, William R., Villadangos, Jose A.
Publicado em 2006

A Novel HLA-B18 Restricted CD8+ T Cell Epitope Is Efficiently Cross-Presented by Dendritic Cells from Soluble Tumor Antigen

Por Zhao, Rona Y., Mifsud, Nicole A., Xiao, Kun, Chan, Kok-Fei, Oveissi, Sara, Jackson, Heather M., Dimopoulos, Nektaria, Guillaume, Philippe, Knights, Ashley J., Lowen, Tamara, Robson, Neil C., Russell, Sarah E., Scotet, Emmanuel, Davis, Ian D., Maraskovsky, Eugene, Cebon, Jonathan, Luescher, Immanuel F., Chen, Weisan
Publicado em 2012

Immunodominant CD4(+) responses identified in a patient vaccinated with full-length NY-ESO-1 formulated with ISCOMATRIX adjuvant

Por Chen, Qiyuan, Jackson, Heather, Parente, Phillip, Luke, Tina, Rizkalla, Mark, Tai, Tsin Yee, Zhu, He-Cheng, Mifsud, Nicole A., Dimopoulos, Nektaria, Masterman, Kelly-Anne, Hopkins, Wendie, Goldie, Heather, Maraskovsky, Eugene, Green, Simon, Miloradovic, Lena, McCluskey, James, Old, Lloyd J., Davis, Ian D., Cebon, Jonathan, Chen, Weisan
Publicado em 2004

The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement

Por Caminschi, Irina, Proietto, Anna I., Ahmet, Fatma, Kitsoulis, Susie, Shin Teh, Joo, Lo, Jennifer C. Y., Rizzitelli, Alexandra, Wu, Li, Vremec, David, van Dommelen, Serani L. H., Campbell, Ian K., Maraskovsky, Eugene, Braley, Hal, Davey, Gayle M., Mottram, Patricia, van de Velde, Nicholas, Jensen, Kent, Lew, Andrew M., Wright, Mark D., Heath, William R., Shortman, Ken, Lahoud, Mireille H.
Publicado em 2008

Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad integrated antibody and CD4+ and CD8+ T cell responses in humans

Por Davis, Ian D., Chen, Weisan, Jackson, Heather, Parente, Phillip, Shackleton, Mark, Hopkins, Wendie, Chen, Qiyuan, Dimopoulos, Nektaria, Luke, Tina, Murphy, Roger, Scott, Andrew M., Maraskovsky, Eugene, McArthur, Grant, MacGregor, Duncan, Sturrock, Sue, Tai, Tsin Yee, Green, Simon, Cuthbertson, Andrew, Maher, Darryl, Miloradovic, Lena, Mitchell, Susan V., Ritter, Gerd, Jungbluth, Achim A., Chen, Yao-Tseng, Gnjatic, Sacha, Hoffman, Eric W., Old, Lloyd J., Cebon, Jonathan S.
Publicado em 2004

Results of a randomized, double-blind phase II clinical trial of NY-ESO-1 vaccine with ISCOMATRIX adjuvant versus ISCOMATRIX alone in participants with high-risk resected melanoma

Por Cebon, Jonathan S, Gore, Martin, Thompson, John F, Davis, Ian D, McArthur, Grant A, Walpole, Euan, Smithers, Mark, Cerundolo, Vincenzo, Dunbar, P Rod, MacGregor, Duncan, Fisher, Cyril, Millward, Michael, Nathan, Paul, Findlay, Michael P N, Hersey, Peter, Evans, T R Jeffry, Ottensmeier, Christian Hermann, Marsden, Jeremy, Dalgleish, Angus G, Corrie, Pippa G, Maria, Marples, Brimble, Margaret, Williams, Geoff, Winkler, Sintia, Jackson, Heather M, Endo-Munoz, Liliana, Tutuka, Candani S A, Venhaus, Ralph, Old, Lloyd J, Haack, Dennis, Maraskovsky, Eugene, Behren, Andreas, Chen, Weisan
Publicado no J Immunother Cancer (2020)