A Novel HLA-B18 Restricted CD8+ T Cell Epitope Is Efficiently Cross-Presented by Dendritic Cells from Soluble Tumor Antigen

NY-ESO-1 has been a major target of many immunotherapy trials because it is expressed by various cancers and is highly immunogenic. In this study, we have identified a novel HLA-B*1801-restricted CD8(+) T cell epitope, NY-ESO-1(88–96) (LEFYLAMPF) and compared its direct- and cross-presentation to th...

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Détails bibliographiques
Auteurs principaux: Zhao, Rona Y., Mifsud, Nicole A., Xiao, Kun, Chan, Kok-Fei, Oveissi, Sara, Jackson, Heather M., Dimopoulos, Nektaria, Guillaume, Philippe, Knights, Ashley J., Lowen, Tamara, Robson, Neil C., Russell, Sarah E., Scotet, Emmanuel, Davis, Ian D., Maraskovsky, Eugene, Cebon, Jonathan, Luescher, Immanuel F., Chen, Weisan
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435279/
https://ncbi.nlm.nih.gov/pubmed/22970293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044707
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