Bone Cancer Pain: From Mechanism to Therapy

Por Mantyh, Patrick W.
Publicado em 2014

The neurobiology of skeletal pain

Por Mantyh, Patrick W.
Publicado no Eur J Neurosci (2014)

Sensory and sympathetic nerve fibers undergo sprouting and neuroma formation in the painful arthritic joint of geriatric mice

Por Jimenez-Andrade, Juan M, Mantyh, Patrick W
Publicado em 2012

Sclerostin Immunoreactivity Increases in Cortical Bone Osteocytes and Decreases in Articular Cartilage Chondrocytes in Aging Mice

Por Thompson, Michelle L., Jimenez-Andrade, Juan Miguel, Mantyh, Patrick W.
Publicado no J Histochem Cytochem (2015)

Immunohistochemical localization of nerve growth factor, tropomyosin receptor kinase A, and p75 in the bone and articular cartilage of the mouse femur

Por Chartier, Stephane R, Mitchell, Stefanie AT, Majuta, Lisa A, Mantyh, Patrick W
Publicado no Mol Pain (2017)

Preventing painful age-related bone fractures: Anti-sclerostin therapy builds cortical bone and increases the proliferation of osteogenic cells in the periosteum of the geriatric m...

Por Thompson, Michelle L, Chartier, Stephane R, Mitchell, Stefanie A, Mantyh, Patrick W
Publicado no Mol Pain (2016)

Antagonism of Nerve Growth Factor-TrkA Signaling and the Relief of Pain

Por Mantyh, Patrick W., Koltzenburg, Martin, Mendell, Lorne M., Tive, Leslie, Shelton, David L.
Publicado em 2011

Organization of a unique net-like meshwork of CGRP+ sensory fibers in the mouse periosteum: Implications for the generation and maintenance of bone fracture pain

Por Martin, Carl D., Jimenez-Andrade, Juan Miguel, Ghilardi, Joseph R., Mantyh, Patrick W.
Publicado no Neurosci Lett (2007)

New advances in musculoskeletal pain

Por Bove, Susan E., Flatters, Sarah J.L., Inglis, Julia J., Mantyh, Patrick W.
Publicado no Brain Res Rev (2008)

Orthopedic surgery and bone fracture pain are both significantly attenuated by sustained blockade of nerve growth factor

Por Majuta, Lisa A., Longo, Geraldine, Fealk, Michelle N., McCaffrey, Gwen, Mantyh, Patrick W.
Publicado no Pain (2015)

AN EVOLVING CELLULAR PATHOLOGY OCCURS IN DORSAL ROOT GANGLIA, PERIPHERAL NERVE AND SPINAL CORD FOLLOWING INTRAVENOUS ADMINISTRATION OF PACLITAXEL IN THE RAT

Por Peters, Christopher M., Jimenez-Andrade, Juan Miguel, Kuskowski, Michael A., Ghilardi, Joseph R., Mantyh, Patrick W.
Publicado em 2007

Preventive or late administration of anti-NGF therapy attenuates tumor-induced nerve sprouting, neuroma formation and cancer pain

Por Jimenez-Andrade, Juan Miguel, Ghilardi, Joseph R., Castaneda-Corral, Gabriela, Kuskowski, Michael A., Mantyh, Patrick W.
Publicado em 2011

Anti-nerve growth factor therapy increases spontaneous day/night activity in mice with orthopedic surgery induced pain

Por Majuta, Lisa A., Guedon, Jean-Marc G., Mitchell, Stefanie A. T., Ossipov, Michael H., Mantyh, Patrick W.
Publicado no Pain (2017)

Mice with cancer-induced bone pain show a marked decline in day/night activity

Por Majuta, Lisa A., Guedon, Jean-Marc G., Mitchell, Stefanie A.T., Kuskowski, Michael A., Mantyh, Patrick W.
Publicado no Pain Rep (2017)

Exuberant sprouting of sensory and sympathetic nerve fibers in nonhealed bone fractures and the generation and maintenance of chronic skeletal pain

Por Chartier, Stephane R., Thompson, Michelle L., Longo, Geraldine, Fealk, Michelle N., Majuta, Lisa A., Mantyh, Patrick W.
Publicado no Pain (2014)

Vascularization of the dorsal root ganglia and peripheral nerve of the mouse: Implications for chemical-induced peripheral sensory neuropathies

Por Jimenez-Andrade, Juan M, Herrera, Monica B, Ghilardi, Joseph R, Vardanyan, Marina, Melemedjian, Ohannes K, Mantyh, Patrick W
Publicado em 2008

NGF blockade at early times during bone cancer development attenuates bone destruction and increases limb use

Por McCaffrey, Gwen, Thompson, Michelle L., Majuta, Lisa, Fealk, Michelle N., Chartier, Stephane, Longo, Geraldine, Mantyh, Patrick W.
Publicado no Cancer Res (2014)

Dissociation between the relief of skeletal pain behaviors and skin hypersensitivity in a model of bone cancer pain

Por Guedon, Jean-Marc G., Longo, Geraldine, Majuta, Lisa A., Thomspon, Michelle L., Fealk, Michelle N., Mantyh, Patrick W.
Publicado no Pain (2016)

Bone cancer pain

Por Jimenez-Andrade, Juan Miguel, Mantyh, William G., Bloom, Aaron P., Ferng, Alice S., Geffre, Christopher P., Mantyh, Patrick W.
Publicado no Ann N Y Acad Sci (2010)

Intravenous Ibandronate Rapidly Reduces Pain, Neurochemical Indices of Central Sensitization, Tumor Burden, and Skeletal Destruction in a Mouse Model of Bone Cancer

Por Halvorson, Kyle G., Sevcik, Molly A., Ghilardi, Joseph R., Sullivan, Lucy J., Koewler, Nathan J., Bauss, Frieder, Mantyh, Patrick W.
Publicado em 2008