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NGF blockade at early times during bone cancer development attenuates bone destruction and increases limb use

Studies in animals and humans show that blockade of nerve growth factor (NGF) attenuates both malignant and non-malignant skeletal pain. While reduction of pain is important, a largely unanswered question is what other benefits NGF blockade might confer in bone cancer patients. Using a mouse graft m...

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書目詳細資料
發表在:Cancer Res
Main Authors: McCaffrey, Gwen, Thompson, Michelle L., Majuta, Lisa, Fealk, Michelle N., Chartier, Stephane, Longo, Geraldine, Mantyh, Patrick W.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253026/
https://ncbi.nlm.nih.gov/pubmed/25287160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1220
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