Clinical translation of genetic predictors for type 2 diabetes

Por Majithia, Amit R., Florez, Jose C.
Publicado em 2009

Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes

Por Grapin-Botton, Anne, Majithia, Amit R., Melton, Douglas A.
Publicado em 2001

Thousands of missing variants in the UK Biobank are recoverable by genome realignment

Por Jia, Tongqiu, Munson, Brenton, Allen, Hana Lango, Ideker, Trey, Majithia, Amit R.
Publicado no Ann Hum Genet (2020)

TOR complex 2 (TORC2) in Dictyostelium suppresses phagocytic nutrient capture independently of TORC1-mediated nutrient sensing

Por Rosel, Daniel, Khurana, Taruna, Majithia, Amit, Huang, Xiuli, Bhandari, Ramanath, Kimmel, Alan R.
Publicado em 2012

Rate of Change of Premeal Glucose Measured by Continuous Glucose Monitoring Predicts Postmeal Glycemic Excursions in Patients With Type 1 Diabetes: Implications for Therapy

Por Majithia, Amit R., Wiltschko, Alexander B., Zheng, Hui, Walford, Geoffrey A., Nathan, David M.
Publicado no J Diabetes Sci Technol (2017)

Combinatorial cell-specific regulation of GSK3 directs cell differentiation and polarity in Dictyostelium

Por Kim, Leung, Brzostowski, Joseph, Majithia, Amit, Lee, Nam-Sihk, McMains, Vanessa, Kimmel, Alan R.
Publicado em 2011

Multiplex detection of four pathogenic retroviruses using molecular beacons

Por Vet, Jacqueline A. M., Majithia, Amit R., Marras, Salvatore A. E., Tyagi, Sanjay, Dube, Syamalima, Poiesz, Bernard J., Kramer, Fred Russell
Publicado em 1999

Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes

Por Majithia, Amit R., Flannick, Jason, Shahinian, Peter, Guo, Michael, Bray, Mark-Anthony, Fontanillas, Pierre, Gabriel, Stacey B., Rosen, Evan D., Altshuler, David
Publicado no Proc Natl Acad Sci U S A (2014)

A Virtual Type 2 Diabetes Clinic Using Continuous Glucose Monitoring and Endocrinology Visits

Por Dixon, Ronald F., Zisser, Howard, Layne, Jennifer E., Barleen, Nathan A., Miller, David P., Moloney, Daniel P., Majithia, Amit R., Gabbay, Robert A., Riff, Josh
Publicado no J Diabetes Sci Technol (2019)

Remote Application and Use of Real-Time Continuous Glucose Monitoring by Adults with Type 2 Diabetes in a Virtual Diabetes Clinic

Por Bergenstal, Richard M., Layne, Jennifer E., Zisser, Howard, Gabbay, Robert A., Barleen, Nathan A., Lee, Amy Armento, Majithia, Amit R., Parkin, Christopher G., Dixon, Ronald F.
Publicado no Diabetes Technol Ther (2021)

IGF2BP2/IMP2 Deficient Mice Resist Obesity through enhanced translation of Ucp1 mRNA and other mRNAs encoding Mitochondrial Proteins

Por Dai, Ning, Zhao, Liping, Wrighting, Diedra, Krämer, Dana, Majithia, Amit, Wang, Yanqun, Cracan, Valentin, Borges-Rivera, Diego, Mootha, Vamsi K., Nahrendorf, Matthias, Thorburn, David R., Minichiello, Liliana, Altshuler, David, Avruch, Joseph
Publicado no Cell Metab (2015)

Glycemic Outcomes in Adults With Type 2 Diabetes Participating in a Continuous Glucose Monitor–Driven Virtual Diabetes Clinic: Prospective Trial

Por Majithia, Amit R, Kusiak, Coco M, Armento Lee, Amy, Colangelo, Francis R, Romanelli, Robert J, Robertson, Scott, Miller, David P, Erani, David M, Layne, Jennifer E, Dixon, Ronald F, Zisser, Howard
Publicado no J Med Internet Res (2020)

A pharmacogenetic approach to the treatment of patients with PPARG mutations

Por Agostini, Maura, Schoenmakers, Erik, Beig, Junaid, Fairall, Louise, Szatmari, Istvan, Rajanayagam, Odelia, Muskett, Fred, Adams, Claire, Marais, A. David, O’Rahilly, Stephen, Semple, Robert K., Nagy, Laszlo, Majithia, Amit R., Schwabe, John, Blom, Dirk J., Murphy, Rinki, Chatterjee, Krishna, Savage, David B.
Publicado no Diabetes (2018)

Natural helix 9 mutants of PPARγ differently affect its transcriptional activity

Por Broekema, Marjoleine F., Massink, Maarten P.G., Donato, Cinzia, de Ligt, Joep, Schaarschmidt, Joerg, Borgman, Anouska, Schooneman, Marieke G., Melchers, Diana, Gerding, Martin N., Houtman, René, Bonvin, Alexandre M.J.J., Majithia, Amit R., Monajemi, Houshang, van Haaften, Gijs W., Soeters, Maarten R., Kalkhoven, Eric
Publicado no Mol Metab (2018)

Prospective functional classification of all possible missense variants in PPARG

Por Majithia, Amit R., Tsuda, Ben, Agostini, Maura, Gnanapradeepan, Keerthana, Rice, Robert, Peloso, Gina, Patel, Kashyap A., Zhang, Xiaolan, Broekema, Marjoleine F., Patterson, Nick, Duby, Marc, Sharpe, Ted, Kalkhoven, Eric, Rosen, Evan D., Barroso, Inês, Ellard, Sian, Kathiresan, Sekar, O’Rahilly, Stephen, Chatterjee, Krishna, Florez, Jose C., Mikkelsen, Tarjei, Savage, David B., Altshuler, David
Publicado no Nat Genet (2016)

Discovering metabolic disease gene interactions by correlated effects on cellular morphology

Por Jiao, Yang, Ahmed, Umer, Sim, M.F. Michelle, Bejar, Andrea, Zhang, Xiaolan, Talukder, M. Mesbah Uddin, Rice, Robert, Flannick, Jason, Podgornaia, Anna I., Reilly, Dermot F., Engreitz, Jesse M., Kost-Alimova, Maria, Hartland, Kate, Mercader, Josep-Maria, Georges, Sara, Wagh, Vilas, Tadin-Strapps, Marija, Doench, John G., Edwardson, J. Michael, Rochford, Justin J., Rosen, Evan D., Majithia, Amit R.
Publicado no Mol Metab (2019)

Gene family information facilitates variant interpretation and identification of disease-associated genes in neurodevelopmental disorders

Por Lal, Dennis, May, Patrick, Perez-Palma, Eduardo, Samocha, Kaitlin E., Kosmicki, Jack A., Robinson, Elise B., Møller, Rikke S., Krause, Roland, Nürnberg, Peter, Weckhuysen, Sarah, De Jonghe, Peter, Guerrini, Renzo, Niestroj, Lisa M., Du, Juliana, Marini, Carla, Ware, James S., Kurki, Mitja, Gormley, Padhraig, Tang, Sha, Wu, Sitao, Biskup, Saskia, Poduri, Annapurna, Neubauer, Bernd A., Koeleman, Bobby P. C., Helbig, Katherine L., Weber, Yvonne G., Helbig, Ingo, Majithia, Amit R., Palotie, Aarno, Daly, Mark J.
Publicado no Genome Med (2020)