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Combinatorial cell-specific regulation of GSK3 directs cell differentiation and polarity in Dictyostelium

In Dictyostelium, the interaction of secreted cAMP with specific cell surface receptors regulates the activation/de-activation of GSK3, which mediates developmental cell patterning. In addition, Dictyostelium cells polarize in response to extracellular cAMP, although a potential role for GSK3 in thi...

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Detalhes bibliográficos
Main Authors: Kim, Leung, Brzostowski, Joseph, Majithia, Amit, Lee, Nam-Sihk, McMains, Vanessa, Kimmel, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014631/
https://ncbi.nlm.nih.gov/pubmed/21205787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.055335
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