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TOR complex 2 (TORC2) in Dictyostelium suppresses phagocytic nutrient capture independently of TORC1-mediated nutrient sensing

The TOR protein kinase functions in two distinct complexes, TOR complex 1 (TORC1) and 2 (TORC2). TORC1 is required for growth in response to growth factors, nutrients and the cellular energy state; TORC2 regulates AKT signaling, which can modulate cytoskeletal polarization. In its ecological niche,...

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Detalhes bibliográficos
Main Authors: Rosel, Daniel, Khurana, Taruna, Majithia, Amit, Huang, Xiuli, Bhandari, Ramanath, Kimmel, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269021/
https://ncbi.nlm.nih.gov/pubmed/22266904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.077040
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