Combination Therapies for Lysosomal Storage Diseases: A Complex Answer to a Simple Problem

Por Macauley, Shannon L
Publicado no Pediatr Endocrinol Rev (2016)

Promising CNS-Directed Enzyme Replacement Therapy for Lysosomal Storage Diseases

Por Macauley, Shannon L., Sands, Mark S.
Publicado em 2009

Recent Advances from the Bench Toward the Bedside in Alzheimer's Disease

Por Macauley, Shannon L., Holtzman, David M.
Publicado no EBioMedicine (2015)

The Role of Attenuated Astrocyte Activation in Infantile Neuronal Ceroid Lipofuscinosis

Por Macauley, Shannon L., Pekny, Milos, Sands, Mark S.
Publicado em 2011

Changes in insulin and insulin signaling in Alzheimer’s disease: cause or consequence?

Por Stanley, Molly, Macauley, Shannon L., Holtzman, David M.
Publicado no J Exp Med (2016)

Cerebellar Pathology and Motor Deficits in the Palmitoyl Protein Thioesterase 1-Deficient Mouse

Por Macauley, Shannon L., Wozniak, David F., Kielar, Catherine, Tan, Yun, Cooper, Jonathan D., Sands, Mark S.
Publicado em 2009

Combination small molecule PPT1 mimetic and CNS-directed gene therapy as a treatment for infantile neuronal ceroid lipofuscinosis

Por Roberts, Marie S., Macauley, Shannon L., Wong, Andrew M., Yilmas, Denis, Hohm, Sarah, Cooper, Jonathan D., Sands, Mark S.
Publicado em 2012

Synergistic effects of CNS-directed gene therapy and bone marrow transplantation in the murine model of infantile neuronal ceroid lipofuscinosis

Por Macauley, Shannon L., Roberts, Marie S., Wong, Andrew M., McSloy, Francesca, Reddy, Adarsh S., Cooper, Jonathan D., Sands, Mark S.
Publicado em 2012

Successive neuron loss in the thalamus and cortex in a mouse model of infantile neuronal ceroid lipofuscinosis

Por Kielar, Catherine, Maddox, Lucy, Bible, Ellen, Pontikis, Charlie C, Macauley, Shannon L, Griffey, Megan A, Wong, Michael, Sands, Mark S, Cooper, Jonathan D
Publicado em 2006

Aerobic Glycolysis in the Frontal Cortex Correlates with Memory Performance in Wild-Type Mice But Not the APP/PS1 Mouse Model of Cerebral Amyloidosis

Por Harris, Richard A., Tindale, Lauren, Lone, Asad, Singh, Olivia, Macauley, Shannon L., Stanley, Molly, Holtzman, David M., Bartha, Robert, Cumming, Robert C.
Publicado no J Neurosci (2016)

The Effects of Peripheral and Central High Insulin on Brain Insulin Signaling and Amyloid-β in Young and Old APP/PS1 Mice

Por Stanley, Molly, Macauley, Shannon L., Caesar, Emily E., Koscal, Lauren J., Moritz, Will, Robinson, Grace O., Roh, Joseph, Keyser, Jennifer, Jiang, Hong, Holtzman, David M.
Publicado no J Neurosci (2016)

Hyperglycemia modulates extracellular amyloid-β concentrations and neuronal activity in vivo

Por Macauley, Shannon L., Stanley, Molly, Caesar, Emily E., Yamada, Steven A., Raichle, Marcus E., Perez, Ronaldo, Mahan, Thomas E., Sutphen, Courtney L., Holtzman, David M.
Publicado no J Clin Invest (2015)

An Anti-Neuroinflammatory That Targets Dysregulated Glia Enhances the Efficacy of CNS-Directed Gene Therapy in Murine Infantile Neuronal Ceroid Lipofuscinosis

Por Macauley, Shannon L., Wong, Andrew M.S., Shyng, Charles, Augner, David P., Dearborn, Joshua T., Pearse, Yewande, Roberts, Marie S., Fowler, Stephen C., Cooper, Jonathan D., Watterson, D. Martin, Sands, Mark S.
Publicado em 2014

Molecular correlates of axonal and synaptic pathology in mouse models of Batten disease

Por Kielar, Catherine, Wishart, Thomas M., Palmer, Alice, Dihanich, Sybille, Wong, Andrew M., Macauley, Shannon L., Chan, Chun-Hung, Sands, Mark S., Pearce, David A., Cooper, Jonathan D., Gillingwater, Thomas H.
Publicado em 2009

Bone Marrow Transplantation Augments the Effect of Brain- and Spinal Cord-Directed Adeno-Associated Virus 2/5 Gene Therapy by Altering Inflammation in the Murine Model of Globoid-C...

Por Reddy, Adarsh S., Kim, Joong H., Hawkins-Salsbury, Jacqueline A., Macauley, Shannon L., Tracy, Elisabeth T., Vogler, Carole A., Han, Xialin, Song, Sheng-Kwei, Wozniak, David F., Fowler, Stephen C., Klein, Robyn S., Sands, Mark S.
Publicado em 2011