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The Role of Attenuated Astrocyte Activation in Infantile Neuronal Ceroid Lipofuscinosis
Infantile neuronal ceroid lipofuscinosis (INCL) is an inherited neurodegenerative disorder affecting the CNS during infancy. INCL is caused by mutations in the CLN1 gene that lead to a deficiency in the lysosomal hydrolase, palmitoyl protein thioesterase 1 (PPT1). A murine model of INCL, the PPT1-de...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3218425/ https://ncbi.nlm.nih.gov/pubmed/22031903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3579-11.2011 |
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