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Compromised astrocyte function and survival negatively impact neurons in infantile neuronal ceroid lipofuscinosis
The neuronal ceroid lipofuscinoses (NCLs) are the most common cause of childhood dementia and are invariably fatal. Early localized glial activation occurs in these disorders, and accurately predicts where neuronal loss is most pronounced. Recent evidence suggests that glial dysfunction may contribu...
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| Publicado no: | Acta Neuropathol Commun |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6081811/ https://ncbi.nlm.nih.gov/pubmed/30089511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-018-0575-4 |
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