Lymphoma stem cells: enough evidence to support their existence?

Por Martinez-Climent, Jose A., Fontan, Lorena, Gascoyne, Randy D., Siebert, Reiner, Prosper, Felipe
Publicado em 2010

Co-amplified genes at 8p12 and 11q13 in breast tumors cooperate with two major pathways in oncogenesis

Por Kwek, Serena S., Roy, Ritu, Zhou, Hua, Climent, Joan, Martinez-Climent, Jose A., Fridlyand, Jane, Albertson, Donna G.
Publicado em 2009

A quantitative analysis of genomic instability in lymphoid and plasma cell neoplasms based on the PIG-A gene

Por Araten, David J., Martinez-Climent, Jose A., Perle, Mary Ann, Holm, Eliana, Zamechek, Leah, DiTata, Kimberly, Sanders, Katie J.
Publicado em 2010

Expression profiles of adult T-cell leukemia–lymphoma and associations with clinical responses to zidovudine and interferon α

Por ALIZADEH, ASH A., BOHEN, SEAN P., LOSSOS, CHEN, MARTINEZ-CLIMENT, JOSE A., RAMOS, JUAN CARLOS, CUBEDO-GIL, ELENA, HARRINGTON, WILLIAM J., LOSSOS, IZIDORE S.
Publicado no Leuk Lymphoma (2010)

B-cell leukemia transdifferentiation to macrophage involves reconfiguration of DNA methylation for long-range regulation

Por Bueno-Costa, Alberto, Piñeyro, David, Soler, Marta, Javierre, Biola M., Raurell-Vila, Helena, Subirana-Granés, Marc, Pasquali, Lorenzo, Martinez-Climent, Jose A., Esteller, Manel
Publicado no Leukemia (2019)

Identified hidden genomic changes in mantle cell lymphoma using high resolution single nucleotide polymorphism genomic array

Por Kawamata, Norihiko, Ogawa, Seishi, Gueller, Saskia, Ross, Samuel H., Huynh, Thien, Chen, John, Chang, Andrew, Nabavi-Nouis, Shayan, Megrabian, Nairi, Siebert, Reiner, Martinez-Climent, Jose A., Koeffler, H. Phillip
Publicado no Exp Hematol (2009)

Involvement of miRNAs in the Differentiation of Human Glioblastoma Multiforme Stem-Like Cells

Por Aldaz, Beatriz, Sagardoy, Ainara, Nogueira, Lorena, Guruceaga, Elizabeth, Grande, Lara, Huse, Jason T., Aznar, Maria A., Díez-Valle, Ricardo, Tejada-Solís, Sonia, Alonso, Marta M., Fernandez-Luna, Jose L., Martinez-Climent, Jose A., Malumbres, Raquel
Publicado em 2013

Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma

Por Cubedo, Elena, Gentles, Andrew J., Huang, Chuanxin, Natkunam, Yasodha, Bhatt, Shruti, Lu, Xiaoqing, Jiang, Xiaoyu, Romero-Camarero, Isabel, Freud, Aharon, Zhao, Shuchun, Bacchi, Carlos E., Martínez-Climent, Jose A., Sánchez-García, Isidro, Melnick, Ari, Lossos, Izidore S.
Publicado em 2012

LMO2 expression reflects the different stages of blast maturation and genetic features in B-cell acute lymphoblastic leukemia and predicts clinical outcome

Por Malumbres, Raquel, Fresquet, Vicente, Roman-Gomez, Jose, Bobadilla, Miriam, Robles, Eloy F., Altobelli, Giovanna G., Calasanz, M.ª José, Smeland, Erlend B., Aznar, Maria Angela, Agirre, Xabier, Martin-Palanco, Vanesa, Prosper, Felipe, Lossos, Izidore S., Martinez-Climent, Jose A.
Publicado em 2011

LITAF, a BCL6 target gene, regulates autophagy in mature B-cell lymphomas

Por Bertolo, Cristina, Roa, Sergio, Sagardoy, Ainara, Mena-Varas, Maria, Robles, Eloy F., Martinez-Ferrandis, Jose I., Sagaert, Xavier, Tousseyn, Thomas, Orta, Alberto, Lossos, Izidore S., Amar, Salomon, Natkunam, Yasodha, Briones, Javier, Melnick, Ari, Malumbres, Raquel, Martinez-Climent, Jose A.
Publicado em 2013

Downregulation of FOXP1 is required during germinal center B-cell function

Por Sagardoy, Ainara, Martinez-Ferrandis, Jose I., Roa, Sergio, Bunting, Karen L., Aznar, María Angela, Elemento, Olivier, Shaknovich, Rita, Fontán, Lorena, Fresquet, Vicente, Perez-Roger, Ignacio, Robles, Eloy F., De Smedt, Linde, Sagaert, Xavier, Melnick, Ari, Martinez-Climent, Jose A.
Publicado em 2013

Combined clinical and genomic signatures for the prognosis of early stage non-small cell lung cancer based on gene copy number alterations

Por Aramburu, Ander, Zudaire, Isabel, Pajares, María J., Agorreta, Jackeline, Orta, Alberto, Lozano, María D., Gúrpide, Alfonso, Gómez-Román, Javier, Martinez-Climent, Jose A., Jassem, Jacek, Skrzypski, Marcin, Suraokar, Milind, Behrens, Carmen, Wistuba, Ignacio I., Pio, Ruben, Rubio, Angel, Montuenga, Luis M.
Publicado no BMC Genomics (2015)

A cyclin-D1 interaction with BAX underlies its oncogenic role and potential as a therapeutic target in mantle cell lymphoma

Por Beltran, Elena, Fresquet, Vicente, Martinez-Useros, Javier, Richter-Larrea, Jose A., Sagardoy, Ainara, Sesma, Izaskun, Almada, Luciana L., Montes-Moreno, Santiago, Siebert, Reiner, Gesk, Stefan, Calasanz, Maria J., Malumbres, Raquel, Rieger, Melissa, Prosper, Felipe, Lossos, Izidore S., Piris, Miguel Angel, Fernandez-Zapico, Martin E., Martinez-Climent, Jose A.
Publicado em 2011

DNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features

Por Arribas, Alberto J., Rinaldi, Andrea, Mensah, Afua A., Kwee, Ivo, Cascione, Luciano, Robles, Eloy F., Martinez-Climent, Jose A., Oscier, David, Arcaini, Luca, Baldini, Luca, Marasca, Roberto, Thieblemont, Catherine, Briere, Josette, Forconi, Francesco, Zamò, Alberto, Bonifacio, Massimiliano, Mollejo, Manuela, Facchetti, Fabio, Dirnhofer, Stephan, Ponzoni, Maurilio, Bhagat, Govind, Piris, Miguel A., Gaidano, Gianluca, Zucca, Emanuele, Rossi, Davide, Bertoni, Francesco
Publicado no Blood (2015)

Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation

Por Romero-Camarero, Isabel, Jiang, Xiaoyu, Natkunam, Yasodha, Lu, Xiaoqing, Vicente-Dueñas, Carolina, Gonzalez-Herrero, Ines, Flores, Teresa, Garcia, Juan Luis, McNamara, George, Kunder, Christian, Zhao, Shuchun, Segura, Victor, Fontan, Lorena, Martínez-Climent, Jose A., García-Criado, Francisco Javier, Theis, Jason D., Dogan, Ahmet, Campos-Sánchez, Elena, Green, Michael R., Alizadeh, Ash A., Cobaleda, Cesar, Sánchez-García, Isidro, Lossos, Izidore S.
Publicado em 2013

The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models

Por Martínez-Vélez, Naiara, Garcia-Moure, Marc, Marigil, Miguel, González-Huarriz, Marisol, Puigdelloses, Montse, Gallego Pérez-Larraya, Jaime, Zalacaín, Marta, Marrodán, Lucía, Varela-Guruceaga, Maider, Laspidea, Virginia, Aristu, Jose Javier, Ramos, Luis Isaac, Tejada-Solís, Sonia, Díez-Valle, Ricardo, Jones, Chris, Mackay, Alan, Martínez-Climent, Jose A., García-Barchino, Maria Jose, Raabe, Eric, Monje, Michelle, Becher, Oren J., Junier, Marie Pierre, El-Habr, Elias A., Chneiweiss, Herve, Aldave, Guillermo, Jiang, Hong, Fueyo, Juan, Patiño-García, Ana, Gomez-Manzano, Candelaria, Alonso, Marta M.
Publicado no Nat Commun (2019)

Expression of MALT1 oncogene in hematopoietic stem/progenitor cells recapitulates the pathogenesis of human lymphoma in mice

Por Vicente-Dueñas, Carolina, Fontán, Lorena, Gonzalez-Herrero, Ines, Romero-Camarero, Isabel, Segura, Victor, Aznar, M. Angela, Alonso-Escudero, Esther, Campos-Sanchez, Elena, Ruiz-Roca, Lucía, Barajas-Diego, Marcos, Sagardoy, Ainara, Martinez-Ferrandis, Jose I., Abollo-Jimenez, Fernando, Bertolo, Cristina, Peñuelas, Ivan, Garcia-Criado, Francisco J., García-Cenador, María B., Tousseyn, Thomas, Agirre, Xabier, Prosper, Felipe, Garcia-Bragado, Federico, McPhail, Ellen D., Lossos, Izidore S., Du, Ming-Qing, Flores, Teresa, Hernandez-Rivas, Jesus M., Gonzalez, Marcos, Salar, Antonio, Bellosillo, Beatriz, Conde, Eulogio, Siebert, Reiner, Sagaert, Xavier, Cobaleda, Cesar, Sanchez-Garcia, Isidro, Martinez-Climent, Jose A.
Publicado em 2012

Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics

Por Robles, Eloy F., Mena-Varas, Maria, Barrio, Laura, Merino-Cortes, Sara V., Balogh, Péter, Du, Ming-Qing, Akasaka, Takashi, Parker, Anton, Roa, Sergio, Panizo, Carlos, Martin-Guerrero, Idoia, Siebert, Reiner, Segura, Victor, Agirre, Xabier, Macri-Pellizeri, Laura, Aldaz, Beatriz, Vilas-Zornoza, Amaia, Zhang, Shaowei, Moody, Sarah, Calasanz, Maria Jose, Tousseyn, Thomas, Broccardo, Cyril, Brousset, Pierre, Campos-Sanchez, Elena, Cobaleda, Cesar, Sanchez-Garcia, Isidro, Fernandez-Luna, Jose Luis, Garcia-Muñoz, Ricardo, Pena, Esther, Bellosillo, Beatriz, Salar, Antonio, Baptista, Maria Joao, Hernandez-Rivas, Jesús Maria, Gonzalez, Marcos, Terol, Maria Jose, Climent, Joan, Ferrandez, Antonio, Sagaert, Xavier, Melnick, Ari M., Prosper, Felipe, Oscier, David G., Carrasco, Yolanda R., Dyer, Martin J. S., Martinez-Climent, Jose A.
Publicado no Nat Commun (2016)