The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models

Pediatric high-grade glioma (pHGG) and diffuse intrinsic pontine gliomas (DIPGs) are aggressive pediatric brain tumors in desperate need of a curative treatment. Oncolytic virotherapy is emerging as a solid therapeutic approach. Delta-24-RGD is a replication competent adenovirus engineered to replic...

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Publicado en:Nat Commun
Autores principales: Martínez-Vélez, Naiara, Garcia-Moure, Marc, Marigil, Miguel, González-Huarriz, Marisol, Puigdelloses, Montse, Gallego Pérez-Larraya, Jaime, Zalacaín, Marta, Marrodán, Lucía, Varela-Guruceaga, Maider, Laspidea, Virginia, Aristu, Jose Javier, Ramos, Luis Isaac, Tejada-Solís, Sonia, Díez-Valle, Ricardo, Jones, Chris, Mackay, Alan, Martínez-Climent, Jose A., García-Barchino, Maria Jose, Raabe, Eric, Monje, Michelle, Becher, Oren J., Junier, Marie Pierre, El-Habr, Elias A., Chneiweiss, Herve, Aldave, Guillermo, Jiang, Hong, Fueyo, Juan, Patiño-García, Ana, Gomez-Manzano, Candelaria, Alonso, Marta M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538754/
https://ncbi.nlm.nih.gov/pubmed/31138805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10043-0
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