Development of a DIPG Orthotopic Model in Mice Using an Implantable Guide-Screw System

OBJECTIVE: In this work we set to develop and to validate a new in vivo frameless orthotopic Diffuse Intrinsic Pontine Glioma (DIPG) model based in the implantation of a guide-screw system. METHODS: It consisted of a guide-screw also called bolt, a Hamilton syringe with a 26-gauge needle and an insu...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Marigil, Miguel, Martinez-Velez, Naiara, Domínguez, Pablo D., Idoate, Miguel Angel, Xipell, Enric, Patiño-García, Ana, Gonzalez-Huarriz, Marisol, García-Moure, Marc, Junier, Marie-Pierre, Chneiweiss, Hervé, El-Habr, Elías, Diez-Valle, Ricardo, Tejada-Solís, Sonia, Alonso, Marta M.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5249159/
https://ncbi.nlm.nih.gov/pubmed/28107439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170501
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