Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation

The human germinal centre associated lymphoma (HGAL) gene is specifically expressed in germinal centre B-lymphocytes and germinal centre-derived B-cell lymphomas, but its function is largely unknown. Here we demonstrate that HGAL directly binds Syk in B-cells, increases its kinase activity upon B-ce...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Romero-Camarero, Isabel, Jiang, Xiaoyu, Natkunam, Yasodha, Lu, Xiaoqing, Vicente-Dueñas, Carolina, Gonzalez-Herrero, Ines, Flores, Teresa, Garcia, Juan Luis, McNamara, George, Kunder, Christian, Zhao, Shuchun, Segura, Victor, Fontan, Lorena, Martínez-Climent, Jose A., García-Criado, Francisco Javier, Theis, Jason D., Dogan, Ahmet, Campos-Sánchez, Elena, Green, Michael R., Alizadeh, Ash A., Cobaleda, Cesar, Sánchez-García, Isidro, Lossos, Izidore S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545406/
https://ncbi.nlm.nih.gov/pubmed/23299888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2334
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items