DNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features

Splenic marginal zone lymphoma is a rare lymphoma. Loss of 7q31 and somatic mutations affecting the NOTCH2 and KLF2 genes are the commonest genomic aberrations. Epigenetic changes can be pharmacologically reverted; therefore, identification of groups of patients with specific epigenomic alterations...

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書誌詳細
出版年:Blood
主要な著者: Arribas, Alberto J., Rinaldi, Andrea, Mensah, Afua A., Kwee, Ivo, Cascione, Luciano, Robles, Eloy F., Martinez-Climent, Jose A., Oscier, David, Arcaini, Luca, Baldini, Luca, Marasca, Roberto, Thieblemont, Catherine, Briere, Josette, Forconi, Francesco, Zamò, Alberto, Bonifacio, Massimiliano, Mollejo, Manuela, Facchetti, Fabio, Dirnhofer, Stephan, Ponzoni, Maurilio, Bhagat, Govind, Piris, Miguel A., Gaidano, Gianluca, Zucca, Emanuele, Rossi, Davide, Bertoni, Francesco
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2015
主題:
Lymphoid Neoplasia
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416938/
https://ncbi.nlm.nih.gov/pubmed/25612624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-08-596247
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