RNA Processing and mRNA Surveillance in Monogenic Diabetes

Por Locke, Jonathan M., Harries, Lorna W.
Publicado em 2008

A rare SNP in pre-miR-34a is associated with increased levels of miR-34a in pancreatic beta cells

Por Locke, Jonathan M., Lango Allen, Hana, Harries, Lorna W.
Publicado em 2013

A cautionary tale: the non-causal association between type 2 diabetes risk SNP, rs7756992, and levels of non-coding RNA, CDKAL1-v1

Por Locke, Jonathan M., Wei, Fan-Yan, Tomizawa, Kazuhito, Weedon, Michael N., Harries, Lorna W.
Publicado no Diabetologia (2015)

The splice site variant rs11078928 may be associated with a genotype-dependent alteration in expression of GSDMB transcripts

Por Morrison, Faer S, Locke, Jonathan M, Wood, Andrew R, Tuke, Marcus, Pasko, Dorota, Murray, Anna, Frayling, Tim, Harries, Lorna W
Publicado em 2013

Role of microRNAs in the age-associated decline of pancreatic beta cell function in rat islets

Por Tugay, Ksenia, Guay, Claudiane, Marques, Ana C., Allagnat, Florent, Locke, Jonathan M., Harries, Lorna W., Rutter, Guy A., Regazzi, Romano
Publicado no Diabetologia (2015)

Genome-Wide Homozygosity Analysis Reveals HADH Mutations as a Common Cause of Diazoxide-Responsive Hyperinsulinemic-Hypoglycemia in Consanguineous Pedigrees

Por Flanagan, Sarah E., Patch, Ann-Marie, Locke, Jonathan M., Akcay, Teoman, Simsek, Enver, Alaei, Mohammadreza, Yekta, Zeinab, Desai, Meena, Kapoor, Ritika R., Hussain, Khalid, Ellard, Sian
Publicado em 2011

The common HNF1A variant I27L is a modifier of age at diabetes diagnosis in HNF1A-MODY individuals

Por Locke, Jonathan M, Saint-Martin, Cécile, Laver, Thomas W, Patel, Kashyap A, Wood, Andrew R, Sharp, Seth A, Ellard, Sian, Bellanné-Chantelot, Christine, Hattersley, Andrew T, Harries, Lorna W, Weedon, Michael N
Publicado no Diabetes (2018)

Development and Standardization of an Improved Type 1 Diabetes Genetic Risk Score for Use in Newborn Screening and Incident Diagnosis

Por Sharp, Seth A., Rich, Stephen S., Wood, Andrew R., Jones, Samuel E., Beaumont, Robin N., Harrison, James W., Schneider, Darius A., Locke, Jonathan M., Tyrrell, Jess, Weedon, Michael N., Hagopian, William A., Oram, Richard A.
Publicado no Diabetes Care (2019)

Loss of MANF Causes Childhood-Onset Syndromic Diabetes Due to Increased Endoplasmic Reticulum Stress

Por Montaser, Hossam, Patel, Kashyap A., Balboa, Diego, Ibrahim, Hazem, Lithovius, Väinö, Näätänen, Anna, Chandra, Vikash, Demir, Korcan, Acar, Sezer, Ben-Omran, Tawfeg, Colclough, Kevin, Locke, Jonathan M., Wakeling, Matthew, Lindahl, Maria, Hattersley, Andrew T., Saarimäki-Vire, Jonna, Otonkoski, Timo
Publicado no Diabetes (2021)

Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis

Por Garin, Intza, Edghill, Emma L., Akerman, Ildem, Rubio-Cabezas, Oscar, Rica, Itxaso, Locke, Jonathan M., Maestro, Miguel Angel, Alshaikh, Adnan, Bundak, Ruveyde, del Castillo, Gabriel, Deeb, Asma, Deiss, Dorothee, Fernandez, Juan M., Godbole, Koumudi, Hussain, Khalid, O’Connell, Michele, Klupa, Thomasz, Kolouskova, Stanislava, Mohsin, Fauzia, Perlman, Kusiel, Sumnik, Zdenek, Rial, Jose M., Ugarte, Estibaliz, Vasanthi, Thiruvengadam, Johnstone, Karen, Flanagan, Sarah E., Martínez, Rosa, Castaño, Carlos, Patch, Ann-Marie, Fernández-Rebollo, Eduardo, Raile, Klemens, Morgan, Noel, Harries, Lorna W., Castaño, Luis, Ellard, Sian, Ferrer, Jorge, de Nanclares, Guiomar Perez, Hattersley, Andrew T.
Publicado em 2010