Role of microRNAs in the age-associated decline of pancreatic beta cell function in rat islets

AIMS/HYPOTHESIS: Ageing can lead to reduced insulin sensitivity and loss of pancreatic beta cell function, predisposing individuals to the development of diabetes. The aim of this study was to assess the contribution of microRNAs (miRNAs) to age-associated beta cell dysfunction. METHODS: The global...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Tugay, Ksenia, Guay, Claudiane, Marques, Ana C., Allagnat, Florent, Locke, Jonathan M., Harries, Lorna W., Rutter, Guy A., Regazzi, Romano
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670458/
https://ncbi.nlm.nih.gov/pubmed/26474776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-015-3783-5
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