Role of microRNAs in the age-associated decline of pancreatic beta cell function in rat islets

AIMS/HYPOTHESIS: Ageing can lead to reduced insulin sensitivity and loss of pancreatic beta cell function, predisposing individuals to the development of diabetes. The aim of this study was to assess the contribution of microRNAs (miRNAs) to age-associated beta cell dysfunction. METHODS: The global...

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Vydáno v:Diabetologia
Hlavní autoři: Tugay, Ksenia, Guay, Claudiane, Marques, Ana C., Allagnat, Florent, Locke, Jonathan M., Harries, Lorna W., Rutter, Guy A., Regazzi, Romano
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670458/
https://ncbi.nlm.nih.gov/pubmed/26474776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-015-3783-5
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