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Age-related islet inflammation marks the proliferative decline of pancreatic beta-cells in zebrafish
The pancreatic islet, a cellular community harboring the insulin-producing beta-cells, is known to undergo age-related alterations. However, only a handful of signals associated with aging have been identified. By comparing beta-cells from younger and older zebrafish, here we show that the aging isl...
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Publicado no: | eLife |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
eLife Sciences Publications, Ltd
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5943033/ https://ncbi.nlm.nih.gov/pubmed/29624168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32965 |
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