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Modelling pancreatic β-cell inflammation in zebrafish identifies the natural product wedelolactone for human islet protection
Islet inflammation and cytokine production are implicated in pancreatic β-cell dysfunction and diabetes pathogenesis. However, we lack therapeutics to protect the insulin-producing β-cells from inflammatory damage. Closing this clinical gap requires the establishment of new disease models of islet i...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Company of Biologists
2019-01-01
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Colecção: | Disease Models & Mechanisms |
Assuntos: | |
Acesso em linha: | http://dmm.biologists.org/content/12/1/dmm036004 |
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