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Age-related islet inflammation marks the proliferative decline of pancreatic beta-cells in zebrafish

The pancreatic islet, a cellular community harboring the insulin-producing beta-cells, is known to undergo age-related alterations. However, only a handful of signals associated with aging have been identified. By comparing beta-cells from younger and older zebrafish, here we show that the aging isl...

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Pubblicato in:eLife
Autori principali: Janjuha, Sharan, Singh, Sumeet Pal, Tsakmaki, Anastasia, Mousavy Gharavy, S Neda, Murawala, Priyanka, Konantz, Judith, Birke, Sarah, Hodson, David J, Rutter, Guy A, Bewick, Gavin A, Ninov, Nikolay
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943033/
https://ncbi.nlm.nih.gov/pubmed/29624168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32965
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