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Different developmental histories of beta-cells generate functional and proliferative heterogeneity during islet growth
The proliferative and functional heterogeneity among seemingly uniform cells is a universal phenomenon. Identifying the underlying factors requires single-cell analysis of function and proliferation. Here we show that the pancreatic beta-cells in zebrafish exhibit different growth-promoting and func...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5610262/ https://ncbi.nlm.nih.gov/pubmed/28939870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00461-3 |
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