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Distinct Levels of Reactive Oxygen Species Coordinate Metabolic Activity with Beta-cell Mass Plasticity

The pancreatic beta-cells control glucose homeostasis by secreting insulin in response to nutrient intake. The number of beta-cells is under tight metabolic control, as this number increases with higher nutrient intake. However, the signaling pathways matching nutrition with beta-cell mass plasticit...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ahmed Alfar, Ezzaldin, Kirova, Dilyana, Konantz, Judith, Birke, Sarah, Mansfeld, Jörg, Ninov, Nikolay
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484671/
https://ncbi.nlm.nih.gov/pubmed/28652605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03873-9
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