Clinical and research uses of genetic risk scores in type 1 diabetes

le Sharp, Seth A, Weedon, Michael N, Hagopian, William A, Oram, Richard A
Foilsithe in Curr Opin Genet Dev (2018)

Type 1 diabetes genetic risk score is discriminative of diabetes in non-Europeans: evidence from a study in India

le Harrison, James W., Tallapragada, Divya Sri Priyanka, Baptist, Alma, Sharp, Seth A., Bhaskar, Seema, Jog, Kalpana S., Patel, Kashyap A., Weedon, Michael N., Chandak, Giriraj R., Yajnik, Chittaranjan S., Oram, Richard A.
Foilsithe in Sci Rep (2020)

IgA Nephropathy Genetic Risk Score to Estimate the Prevalence of IgA Nephropathy in UK Biobank

le Sukcharoen, Kittiya, Sharp, Seth A., Thomas, Nicholas J., Kimmitt, Robert A., Harrison, Jamie, Bingham, Coralie, Mozere, Monika, Weedon, Michael N., Tyrrell, Jessica, Barratt, Jonathan, Gale, Daniel P., Oram, Richard A.
Foilsithe in Kidney Int Rep (2020)

The common HNF1A variant I27L is a modifier of age at diabetes diagnosis in HNF1A-MODY individuals

le Locke, Jonathan M, Saint-Martin, Cécile, Laver, Thomas W, Patel, Kashyap A, Wood, Andrew R, Sharp, Seth A, Ellard, Sian, Bellanné-Chantelot, Christine, Hattersley, Andrew T, Harries, Lorna W, Weedon, Michael N
Foilsithe in Diabetes (2018)

Development and Standardization of an Improved Type 1 Diabetes Genetic Risk Score for Use in Newborn Screening and Incident Diagnosis

le Sharp, Seth A., Rich, Stephen S., Wood, Andrew R., Jones, Samuel E., Beaumont, Robin N., Harrison, James W., Schneider, Darius A., Locke, Jonathan M., Tyrrell, Jess, Weedon, Michael N., Hagopian, William A., Oram, Richard A.
Foilsithe in Diabetes Care (2019)

A Combined Risk Score enhances prediction of Type 1 Diabetes Among Susceptible Children

le Ferrat, Lauric A., Vehik, Kendra, Sharp, Seth A., Lernmark, Åke, Rewers, Marian J., She, Jin-Xiong, Ziegler, Anette-G., Toppari, Jorma, Akolkar, Beena, Krischer, Jeffrey P., Weedon, Michael N., Oram, Richard A., Hagopian, William A.
Foilsithe in Nat Med (2020)

Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour

le Jones, Samuel E., van Hees, Vincent T., Mazzotti, Diego R., Marques-Vidal, Pedro, Sabia, Séverine, van der Spek, Ashley, Dashti, Hassan S., Engmann, Jorgen, Kocevska, Desana, Tyrrell, Jessica, Beaumont, Robin N., Hillsdon, Melvyn, Ruth, Katherine S., Tuke, Marcus A., Yaghootkar, Hanieh, Sharp, Seth A., Ji, Yingjie, Harrison, Jamie W., Freathy, Rachel M., Murray, Anna, Luik, Annemarie I., Amin, Najaf, Lane, Jacqueline M., Saxena, Richa, Rutter, Martin K., Tiemeier, Henning, Kutalik, Zoltán, Kumari, Meena, Frayling, Timothy M., Weedon, Michael N., Gehrman, Philip R., Wood, Andrew R.
Foilsithe in Nat Commun (2019)

Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms

le Jones, Samuel E., Lane, Jacqueline M., Wood, Andrew R., van Hees, Vincent T., Tyrrell, Jessica, Beaumont, Robin N., Jeffries, Aaron R., Dashti, Hassan S., Hillsdon, Melvyn, Ruth, Katherine S., Tuke, Marcus A., Yaghootkar, Hanieh, Sharp, Seth A., Jie, Yingjie, Thompson, William D., Harrison, Jamie W., Dawes, Amy, Byrne, Enda M., Tiemeier, Henning, Allebrandt, Karla V., Bowden, Jack, Ray, David W., Freathy, Rachel M., Murray, Anna, Mazzotti, Diego R., Gehrman, Philip R., Lawlor, Debbie A., Frayling, Timothy M., Rutter, Martin K., Hinds, David A., Saxena, Richa, Weedon, Michael N.
Foilsithe in Nat Commun (2019)