The Sequence-Activity Relationship between Metallo-β-Lactamases IMP-1, IMP-6, and IMP-25 Suggests an Evolutionary Adaptation to Meropenem Exposure

por Liu, Eleanor M., Pegg, Kevin M., Oelschlaeger, Peter
Publicado 2012

Biochemical Characterization of IMP-30, a Metallo-β-Lactamase with Enhanced Activity toward Ceftazidime

por Pegg, Kevin M., Liu, Eleanor M., LaCuran, Alecander E., Oelschlaeger, Peter
Publicado 2013

Meropenem and Chromacef Intermediates Observed in IMP-25 Metallo-β-Lactamase-Catalyzed Hydrolysis

por Oelschlaeger, Peter, Aitha, Mahesh, Yang, Hao, Kang, Joon S., Zhang, Antonia L., Liu, Eleanor M., Buynak, John D., Crowder, Michael W.
Publicado en Antimicrob Agents Chemother (2015)

Understanding the determinants of substrate specificity in IMP family metallo-β-lactamases: The importance of residue 262

por Pegg, Kevin M, Liu, Eleanor M, George, Alex C, LaCuran, Alecander E, Bethel, Christopher R, Bonomo, Robert A, Oelschlaeger, Peter
Publicado en Protein Sci (2014)

Elucidating the Role of Residue 67 in IMP-Type Metallo-β-Lactamase Evolution

por LaCuran, Alecander E., Pegg, Kevin M., Liu, Eleanor M., Bethel, Christopher R., Ai, Ni, Welsh, William J., Bonomo, Robert A., Oelschlaeger, Peter
Publicado en Antimicrob Agents Chemother (2015)