The Sequence-Activity Relationship between Metallo-β-Lactamases IMP-1, IMP-6, and IMP-25 Suggests an Evolutionary Adaptation to Meropenem Exposure

Autor Liu, Eleanor M., Pegg, Kevin M., Oelschlaeger, Peter
Vydáno 2012

Biochemical Characterization of IMP-30, a Metallo-β-Lactamase with Enhanced Activity toward Ceftazidime

Autor Pegg, Kevin M., Liu, Eleanor M., LaCuran, Alecander E., Oelschlaeger, Peter
Vydáno 2013

Meropenem and Chromacef Intermediates Observed in IMP-25 Metallo-β-Lactamase-Catalyzed Hydrolysis

Autor Oelschlaeger, Peter, Aitha, Mahesh, Yang, Hao, Kang, Joon S., Zhang, Antonia L., Liu, Eleanor M., Buynak, John D., Crowder, Michael W.
Vydáno v Antimicrob Agents Chemother (2015)

Understanding the determinants of substrate specificity in IMP family metallo-β-lactamases: The importance of residue 262

Autor Pegg, Kevin M, Liu, Eleanor M, George, Alex C, LaCuran, Alecander E, Bethel, Christopher R, Bonomo, Robert A, Oelschlaeger, Peter
Vydáno v Protein Sci (2014)

Elucidating the Role of Residue 67 in IMP-Type Metallo-β-Lactamase Evolution

Autor LaCuran, Alecander E., Pegg, Kevin M., Liu, Eleanor M., Bethel, Christopher R., Ai, Ni, Welsh, William J., Bonomo, Robert A., Oelschlaeger, Peter
Vydáno v Antimicrob Agents Chemother (2015)