Melanoma Epigenetics: Novel Mechanisms, Markers, and Medicines

Por Lee, Jonathan J., Murphy, George F., Lian, Christine G.
Publicado no Lab Invest (2014)

Diagnostic Immunohistochemistry in Cutaneous Neoplasia: An Update

Por Compton, Leigh A., Murphy, George F., Lian, Christine G.
Publicado no Dermatopathology (Basel) (2015)

Giant Pyogenic Granuloma in a Patient with Chronic Lymphocytic Leukemia

Por Plovanich, Molly, Tsibris, Hillary C., Lian, Christine G., Mostaghimi, Arash
Publicado no Case Rep Dermatol (2014)

Unilateral Axillary Pseudochromhidrosis-like Lesion Caused by Pediculosis Pubis

Por Wang, Tao, Liang, Si, Liu, Yue-Hua, Lian, Christine Guo
Publicado no Chin Med J (Engl) (2016)

Staphylococcal Scalded Skin Syndrome in an Adult on Chemotherapy

Por Lee, Jonathan J., Tsibris, Hillary C., Mostaghimi, Arash, Lian, Christine G.
Publicado no Dermatopathology (Basel) (2014)

Loss of the epigenetic mark, 5-Hydroxymethylcytosine, correlates with small cell/nevoid subpopulations and assists in microstaging of human melanoma

Por Lee, Jonathan J., Cook, Martin, Mihm, Martin C., Xu, Shuyun, Zhan, Qian, Wang, Thomas J., Murphy, George F., Lian, Christine G.
Publicado no Oncotarget (2015)

Novel germline ERCC5 mutations identified in a xeroderma pigmentosum complementation group G pedigree

Por Wang, Tao, Xu, Chen-chen, Zhou, Xi-ping, Lee, Jonathan J., Shen, Jun, Lian, Bill Q., Liu, Yue-Hua, Lian, Christine Guo
Publicado no JAAD Case Rep (2015)

5-Hydroxymethylcytosine Expression in Metastatic Melanoma versus Nodal Nevus in Sentine Lymph Node Biopsies

Por Lee, Jonathan J., Granter, Scott R., Laga, Alvaro C., Saavedra, Arturo, Zhan, Qian, Guo, Weimin, Xu, Shuyun, Murphy, George F., Lian, Christine G.
Publicado no Mod Pathol (2014)

Homozygous ALOXE3 Nonsense Variant Identified in a Patient with Non-Bullous Congenital Ichthyosiform Erythroderma Complicated by Superimposed Bullous Majocchi’s Granuloma: The Cons...

Por Wang, Tao, Xu, Chenchen, Zhou, Xiping, Li, Chunjia, Zhang, Hongbing, Lian, Bill Q., Lee, Jonathan J., Shen, Jun, Liu, Yuehua, Lian, Christine Guo
Publicado no Int J Mol Sci (2015)

Estradiol increases angiotensin II type 1 receptor in hearts of ovariectomized rats

Por Ricchiuti, Vincent, Lian, Christine G., Oestreicher, Eveline M., Tran, Loc, Stone, James R., Yao, Tham, Seely, Ellen W., Williams, Gordon H., Adler, Gail K.
Publicado em 2008

Longitudinal, 3D Imaging of Collagen Remodeling in Murine Hypertrophic Scars In Vivo using Polarization-sensitive Optical Frequency Domain Imaging

Por Lo, William C. Y., Villiger, Martin, Golberg, Alexander, Broelsch, G. Felix, Khan, Saiqa, Lian, Christine G., Austen, William G., Yarmush, Martin, Bouma, Brett E.
Publicado no J Invest Dermatol (2016)

TET2 Negatively Regulates Nestin Expression in Human Melanoma

Por Gomes, Camilla B.F., Zechin, Karina G., Xu, Shuyun, Stelini, Rafael F., Nishimoto, Ines N., Zhan, Qian, Xu, Ting, Qin, Gungwei, Treister, Nathaniel S., Murphy, George F., Lian, Christine G.
Publicado no Am J Pathol (2016)

Loss of function mutation in LOX causes thoracic aortic aneurysm and dissection in humans

Por Lee, Vivian S., Halabi, Carmen M., Hoffman, Erin P., Carmichael, Nikkola, Leshchiner, Ignaty, Lian, Christine G., Bierhals, Andrew J., Vuzman, Dana, Mecham, Robert P., Frank, Natasha Y., Stitziel, Nathan O.
Publicado no Proc Natl Acad Sci U S A (2016)

Human LSD2/KDM1b/AOF1 Regulates Gene Transcription by Modulating Intragenic H3K4me2 Methylation

Por Fang, Rui, Barbera, Andrew, Xu, Yufei, Rutenberg, Michael, Leonor, Thiago, Bi, Qing, Lan, Fei, Mei, Pinchao, Yuan, Guo-Cheng, Lian, Christine, Peng, Junmin, Cheng, Dongmei, Sui, Guangchao, Shi, Yang, Shi, Yujiang Geno
Publicado em 2010

Loss of 5-hydroxymethylcytosine correlates with increasing morphologic dysplasia in melanocytic tumors

Por Larson, Allison R., Dresser, Karen, Zhan, Qian, Lezcano, Cecilia, Woda, Bruce A., Yosufi, Benafsha, Thompson, John F., Scolyer, Richard A., Mihm, Martin C., Shi, Yujiang G., Murphy, George F., Lian, Christine Guo
Publicado em 2014

Nestin depletion induces melanoma matrix metalloproteinases and invasion

Por Lee, Chung-Wei, Zhan, Qian, Lezcano, Cecilia, Frank, Markus H., Huang, John, Larson, Allison, Lin, Jennifer Y., Wan, Marilyn T., Lin, Ping-I, Ma, Jie, Kleffel, Sonja, Schatton, Tobias, Lian, Christine G., Murphy, George F.
Publicado no Lab Invest (2014)

Targeted next-generation sequencing reveals high frequency of mutations in epigenetic regulators across treatment-naïve patient melanomas

Por Lee, Jonathan J., Sholl, Lynette M., Lindeman, Neal I., Granter, Scott R., Laga, Alvaro C., Shivdasani, Priyanka, Chin, Gary, Luke, Jason J., Ott, Patrick A., Hodi, F. Stephen, Mihm, Martin C., Lin, Jennifer Y., Werchniak, Andrew E., Haynes, Harley A., Bailey, Nancy, Liu, Robert, Murphy, George F., Lian, Christine G.
Publicado no Clin Epigenetics (2015)

Melanoma cell-intrinsic PD-1 receptor functions promote tumor growth

Por Kleffel, Sonja, Posch, Christian, Barthel, Steven R., Mueller, Hansgeorg, Schlapbach, Christoph, Guenova, Emmanuella, Elco, Christopher P., Lee, Nayoung, Juneja, Vikram R., Zhan, Qian, Lian, Christine G., Thomi, Rahel, Hoetzenecker, Wolfram, Cozzio, Antonio, Dummer, Reinhard, Mihm, Martin C., Flaherty, Keith T., Frank, Markus H., Murphy, George F., Sharpe, Arlene H., Kupper, Thomas S., Schatton, Tobias
Publicado no Cell (2015)

LOSS OF 5-HYDROXYMETHYLCYTOSINE IS AN EPIGENETIC HALLMARK OF MELANOMA

Por Lian, Christine Guo, Xu, Yufei, Ceol, Craig, Wu, Feizhen, Larson, Allison, Dresser, Karen, Xu, Wenji, Tan, Li, Hu, Yeguang, Zhan, Qian, Lee, Chung-wei, Hu, Di, Lian, Bill Q., Kleffel, Sonja, Yang, Yijun, Neiswender, James, Khorasani, Abraham J., Fang, Rui, Lezcano, Cecilia, Duncan, Lyn M., Scolyer, Richard A., Thompson, John F., Kakavand, Hojabr, Houvras, Yariv, Zon, Leonard, Mihm, Martin C., Kaiser, Ursula B., Schatton, Tobias, Woda, Bruce A., Murphy, George F., Shi, Yujiang G.
Publicado em 2012

Identification of a melanoma susceptibility locus and somatic mutation in TET2

Por Song, Fengju, Amos, Christopher I., Lee, Jeffrey E., Lian, Christine G., Fang, Shenying, Liu, Hongliang, MacGregor, Stuart, Iles, Mark M., Law, Matthew H., Lindeman, Neal I., Montgomery, Grant W., Duffy, David L., Cust, Anne E., Jenkins, Mark A., Whiteman, David C., Kefford, Richard F., Giles, Graham G., Armstrong, Bruce K., Aitken, Joanne F., Hopper, John L., Brown, Kevin M., Martin, Nicholas G., Mann, Graham J., Bishop, D.Timothy, Bishop, Julia A.Newton, Kraft, Peter, Qureshi, Abrar A., Kanetsky, Peter A., Hayward, Nicholas K., Hunter, David J., Wei, Qingyi, Han, Jiali
Publicado em 2014