LOSS OF 5-HYDROXYMETHYLCYTOSINE IS AN EPIGENETIC HALLMARK OF MELANOMA

DNA methylation at the 5-position of cytosine (5-mC) is a key epigenetic mark critical for various biological and pathological processes. 5-mC can be converted to 5-hydroxymethylcytosine (5-hmC) by the Ten-Eleven Translocation (TET) family of DNA hydroxylases. Here we report that “loss of 5-hmC” is...

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Detalhes bibliográficos
Main Authors: Lian, Christine Guo, Xu, Yufei, Ceol, Craig, Wu, Feizhen, Larson, Allison, Dresser, Karen, Xu, Wenji, Tan, Li, Hu, Yeguang, Zhan, Qian, Lee, Chung-wei, Hu, Di, Lian, Bill Q., Kleffel, Sonja, Yang, Yijun, Neiswender, James, Khorasani, Abraham J., Fang, Rui, Lezcano, Cecilia, Duncan, Lyn M., Scolyer, Richard A., Thompson, John F., Kakavand, Hojabr, Houvras, Yariv, Zon, Leonard, Mihm, Martin C., Kaiser, Ursula B., Schatton, Tobias, Woda, Bruce A., Murphy, George F., Shi, Yujiang G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770275/
https://ncbi.nlm.nih.gov/pubmed/22980977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.07.033
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