A systems approach to clinical oncology: Focus on breast cancer

Por Abramovitz, Mark, Leyland-Jones, Brian
Publicado em 2006

MYC-xing it up with PIK3CA mutation and resistance to PI3K inhibitors: summit of two giants in breast cancers

Por Dey, Nandini, Leyland-Jones, Brian, De, Pradip
Publicado no Am J Cancer Res (2014)

Dissecting GRB7-mediated signals for proliferation and migration in HER2 overexpressing breast tumor cells: GTP-ase rules

Por Pradip, De, Bouzyk, Mark, Dey, Nandini, Leyland-Jones, Brian
Publicado em 2013

Oncogenic nexus of cancerous inhibitor of protein phosphatase 2A (CIP2A): An oncoprotein with many hands

Por De, Pradip, Carlson, Jennifer, Leyland-Jones, Brian, Dey, Nandini
Publicado em 2014

Role of “oncogenic nexus” of CIP2A in breast oncogenesis: how does it work?

Por De, Pradip, Carlson, Jennifer H, Leyland-Jones, Brian, Dey, Nandini
Publicado no Am J Cancer Res (2015)

Genomic Imbalances Associated with Acquired Resistance to Platinum Analogues

Por Leyland-Jones, Brian, Kelland, Lloyd R., Harrap, Kenneth R., Hiorns, Lynne R.
Publicado em 1999

Tamoxifen metabolic patterns within a glioma patient population treated with high-dose tamoxifen

Por Ducharme, Julie, Fried, Karen, Shenouda, George, Leyland-Jones, Brian, Wainer, Irving W.
Publicado em 1997

Wnt-beta-catenin pathway signals metastasis-associated tumor cell phenotypes in triple negative breast cancers

Por De, Pradip, Carlson, Jennifer H., Wu, Hui, Marcus, Adam, Leyland-Jones, Brian, Dey, Nandini
Publicado no Oncotarget (2016)

RAC1 GTP-ase signals Wnt-beta-catenin pathway mediated integrin-directed metastasis-associated tumor cell phenotypes in triple negative breast cancers

Por De, Pradip, Carlson, Jennifer H., Jepperson, Tyler, Willis, Scooter, Leyland-Jones, Brian, Dey, Nandini
Publicado no Oncotarget (2016)

Differential Activation of Wnt-β-Catenin Pathway in Triple Negative Breast Cancer Increases MMP7 in a PTEN Dependent Manner

Por Dey, Nandini, Young, Brandon, Abramovitz, Mark, Bouzyk, Mark, Barwick, Benjamin, De, Pradip, Leyland-Jones, Brian
Publicado em 2013

Doubling Down on the PI3K-AKT-mTOR Pathway Enhances the Antitumor Efficacy of PARP Inhibitor in Triple Negative Breast Cancer Model beyond BRCA-ness

Por De, Pradip, Sun, Yuling, Carlson, Jennifer H, Friedman, Lori S, Leyland-Jones, Brian R, Dey, Nandini
Publicado em 2014

Erratum to “Doubling Down on the PI3K-AKTmTOR Pathway Enhances the Antitumor Efficacy of PARP Inhibitor in Triple Negative Breast Cancer Model beyond BRCA-ness” [Neoplasia 16 (2014...

Por De, Pradip, Sun, Yuling, Carlson, Jennifer H., Friedman, Lori S., Leyland-Jones, Brian R., Dey, Nandini
Publicado em 2014

Anti-tumor efficacy of BEZ235 is complemented by its anti-angiogenic effects via downregulation of PI3K-mTOR-HIF1alpha signaling in HER2-defined breast cancers

Por Dey, Nandini, Sun, Yuliang, Carlson, Jennifer H, Wu, Hui, Lin, Xiaoqian, Leyland-Jones, Brian, De, Pradip
Publicado no Am J Cancer Res (2016)

Single Gene Prognostic Biomarkers in Ovarian Cancer: A Meta-Analysis

Por Willis, Scooter, Villalobos, Victor M., Gevaert, Olivier, Abramovitz, Mark, Williams, Casey, Sikic, Branimir I., Leyland-Jones, Brian
Publicado no PLoS One (2016)

A Handheld Spectroscopic Device for In Vivo and Intraoperative Tumor Detection: Contrast Enhancement, Detection Sensitivity, and Tissue Penetration

Por Mohs, Aaron M., Mancini, Michael C., Singhal, Sunil, Provenzale, James M., Leyland-Jones, Brian, Wang, May D., Nie, Shuming
Publicado em 2010

Optimization of RNA extraction from FFPE tissues for expression profiling in the DASL assay

Por Abramovitz, Mark, Ordanic-Kodani, Maja, Wang, Yuefang, Li, Zhenhong, Catzavelos, Charles, Bouzyk, Mark, Sledge, George W., Moreno, Carlos S., Leyland-Jones, Brian
Publicado em 2008

Enriched transcription factor signatures in triple negative breast cancer indicates possible targeted therapies with existing drugs

Por Willis, Scooter, De, Pradip, Dey, Nandini, Long, Bradley, Young, Brandon, Sparano, Joseph A., Wang, Victoria, Davidson, Nancy E., Leyland-Jones, Brian R.
Publicado no Meta Gene (2015)

Concordance Between CYP2D6 Genotypes Obtained From Tumor-Derived and Germline DNA

Por Rae, James M., Regan, Meredith M., Thibert, Jacklyn N., Gersch, Christina, Thomas, Dafydd, Leyland-Jones, Brian, Viale, Giuseppe, Pusztai, Lajos, Hayes, Daniel F., Skaar, Todd, Van Poznak, Catherine
Publicado em 2013

Disease-Free Survival According to Degree of HER2 Amplification for Patients Treated With Adjuvant Chemotherapy With or Without 1 Year of Trastuzumab: The HERA Trial

Por Dowsett, Mitch, Procter, Marion, McCaskill-Stevens, Worta, de Azambuja, Evandro, Dafni, Urania, Rueschoff, Josef, Jordan, Bruce, Dolci, Stella, Abramovitz, Mark, Stoss, Oliver, Viale, Giuseppe, Gelber, Richard D., Piccart-Gebhart, Martine, Leyland-Jones, Brian
Publicado em 2009

Molecular Mapping of Tumor Heterogeneity on Clinical Tissue Specimens with Multiplexed Quantum Dots

Por Liu, Jian, Lau, Stephen K., Varma, Vijay A., Moffitt, Richard A., Caldwell, Matthew, Liu, Tao, Young, Andrew N., Petros, John A., Osunkoya, Adeboye O., Krogstad, Tracey, Leyland-Jones, Brian, Wang, May D., Nie, Shuming
Publicado em 2010